Drug Classification NCLEX Questions

Drug Classification NCLEX Questions Related

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A nurse is assisting with caring for a client with cancer who is receiving cisplatin. Select the adverse effects that the nurse monitors for that are associated with this medication. (Select one that does not apply.)

  • A. Tinnitus
  • B. Ototoxicity
  • C. Hyperkalemia
  • D. Hypomagnesemia
Correct Answer: C

Rationale: Cisplatin is an alkylating medication. Alkylating medications are cell cycle phase-nonspecific medications that affect the synthesis of DNA by causing the cross-linking of DNA to inhibit cell reproduction. Cisplatin may cause ototoxicity, tinnitus, hypokalemia, hypocalcemia, hypomagnesemia, and nephrotoxicity. Amifostine (Ethyol) may be administered before cisplatin to reduce the potential for renal toxicity. Correct answers include: 1 (Tinnitus), 2 (Ototoxicity), 5 (Nephrotoxicity), 6 (Hypomagnesemia).

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Serum level of drug is monitored when the patient is on

  • A. Lithium
  • B. Haloperidol
  • C. Diazepam
  • D. Acetazolamide
Correct Answer: A

Rationale: Lithium requires monitoring due to its narrow therapeutic range.

A primary health care provider orders a transdermal drug. When administering this drug, which action by the nurse would be most appropriate?

  • A. Apply next dose to a new site.
  • B. Check the infusion rate.
  • C. Inject only the inner part of the forearm.
  • D. Give small volumes of doses.
Correct Answer: A

Rationale: An important nursing intervention when administrating drugs through the transdermal route is to apply the next dose to a new site. It is important to check the infusion rate every 15 to 30 minutes in patients using infusion controllers or infusion pumps. When using the intradermal route, the inner part of the forearm should be used as the injection site and small volumes of doses should be administered.

A nurse is providing teaching to a client who has type 2 Diabetes Mellitus and is starting Repaglinide. Which of the following statements by the client indicates understanding of the administration of this medication?

  • A. I'll take this medicine with my meals.
  • B. I'll take this medicine 30 minutes before I eat.
  • C. I'll take this medicine just before I go to bed.
  • D. I'll take this medicine as soon as I wake up in the morning.
Correct Answer: B

Rationale: Repaglinide is taken 15-30 minutes before meals to control postprandial glucose.

A potentially life-threatening adverse response to angiotensin-converting enzyme inhibitors is angioedema. Which of the following statements is true about this adverse response?

  • A. Swelling of the tongue or hoarseness are the most common symptoms.
  • B. It appears to be related to the decrease in aldosterone production.
  • C. Presence of a dry, hacky cough indicates a high risk for this adverse response.
  • D. Because it takes time to build up a blood level, it occurs after being on the drug for about 1 week.
Correct Answer: A

Rationale: Angioedema presents with tongue swelling or hoarseness and is not linked to cough or aldosterone.

AH of the following do not cross the blood brain barrier except

  • A. Pyridostigmine
  • B. Neostigmine
  • C. Physostigmine
  • D. Ambenonium
Correct Answer: C

Rationale: Physostigmine, a tertiary amine, crosses the blood-brain barrier; others (quaternary amines) do not.

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