Nokea
Aminoglycosides are most effective against which kind of microorganism?
- A. Aerobic gram-negative bacteria
- B. Anaerobic gram-negative bacteria
- C. Aerobic gram-positive bacteria
- D. Anaerobic gram-positive bacteria
Correct Answer: A
Rationale: Aminoglycosides target aerobic gram-negative bacteria by inhibiting protein synthesis, requiring oxygen-dependent uptake.
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Which of the following statements is correct regarding insulin glargine?
- A. It is primarily used to control postprandial hyperglycemia
- B. It is a 'peakless' insulin
- C. The prolonged duration of activity is due to slow dissociation from albumin
- D. It should not be used in a regimen with insulin lispro or glulisine
Correct Answer: B
Rationale: Insulin glargine is a long-acting, peakless insulin providing steady glucose control.
All nonsteroidal anti-inflammatory drugs (NSAIDS) have an FDA Black Box Warning regarding:
- A. Potential for causing life-threatening GI bleeds
- B. Increased risk of developing systemic arthritis with prolonged use
- C. Risk of life-threatening rashes, including Stevens-Johnson
- D. Potential for transient changes in serum glucose
Correct Answer: A
Rationale: NSAIDs carry a Black Box Warning for GI bleeding risk; rashes or glucose aren't highlighted.
When completing the check to ensure that the right drug is being administered to the client, which of the following should the nurse compare?
- A. Medication
- B. Container label
- C. Medication record
- D. All the above
Correct Answer: D
Rationale: The nurse compares the medication, container label, and medication record and then the MAR as the item is removed from the cart and before the actual administration of the drug.
Which of the following antidiabetic agents acts on the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) nuclear receptor?
- A. acarbose
- B. glyburide
- C. insulin lispro
- D. pioglitazone
Correct Answer: D
Rationale: Pioglitazone is a thiazolidinedione that activates PPAR-gamma, enhancing insulin sensitivity in peripheral tissues.
Following is the example of second generation antihistaminic:
- A. Diphenhydramine
- B. Promethazine
- C. Chlorpheniramine
- D. Cetirizine
Correct Answer: D
Rationale: Cetirizine is a second-generation antihistamine with less sedation due to reduced CNS penetration, unlike first-generation drugs like diphenhydramine, promethazine, and chlorpheniramine.