Nokea
Anaphylactic shock is a:
- A. Type I reaction, called immediate hypersensitivity reaction
- B. Type II reaction, called cytotoxic hypersensitivity reaction
- C. Type III allergic reaction, called immune complex hypersensitivity
- D. Type IV allergic reaction, called delayed hypersensitivity reaction
Correct Answer: A
Rationale: Anaphylactic shock is a Type I immediate hypersensitivity reaction , IgE-mediated, unlike cytotoxic (II), immune complex (III), or delayed (IV).
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Not metabolized in liver
- A. Cimetidine
- B. Phenytoin
- C. Diazepam
- D. Penicillin G
Correct Answer: D
Rationale: Penicillin G is primarily excreted unchanged by the kidneys, unlike the others metabolized by the liver.
Aminoglycosides are most effective against which kind of microorganism?
- A. Aerobic gram-negative bacteria
- B. Anaerobic gram-negative bacteria
- C. Aerobic gram-positive bacteria
- D. Anaerobic gram-positive bacteria
Correct Answer: A
Rationale: Aminoglycosides target aerobic gram-negative bacteria by inhibiting protein synthesis, requiring oxygen-dependent uptake.
An disorder develops lactic acidosis, and nearly dies, as a result of an uncommon but serious adverse response to therapy with an 'endocrine' drug. Which of the following was the most likely cause of this severe problem?
- A. Insulin glargine, prescribed for Type 1 diabetes mellitus
- B. Levothyroxine, prescribed to maintain euthyroid status following thyroidectomy
- C. Metformin, prescribed for Type 2 diabetes mellitus
- D. Propylthiouracil, prescribed for hyperthyroidism
Correct Answer: C
Rationale: Metformin is the most likely cause of lactic acidosis, a rare but life-threatening complication.
A nurse manager is reviewing the facility's policies for IV therapy with the members of his team. The nurse manager should remind the team that which of the following techniques helps minimize the risk of catheter embolism?
- A. Performing hand hygiene before and after IV insertion
- B. Rotating IV sites at least every 72 hr
- C. Minimizing tourniquet time
- D. Avoiding reinserting the needle into an IV catheter
Correct Answer: D
Rationale: Avoiding needle reinsertion prevents shearing of the catheter, reducing embolism risk.
First-generation antihistamines such as loratadine (Claritin) are prescribed for seasonal allergies because they are:
- A. More effective than first-generation antihistamines
- B. Less sedating than the first-generation antihistamines
- C. Prescription products, therefore are covered by insurance
- D. Able to be taken with central nervous system (CNS) sedatives, such as alcohol
Correct Answer: B
Rationale: Loratadine is a second-generation antihistamine, less sedating than first-generation ones; it's not more effective , insurance-driven , or safe with sedatives .