Which of the following causes rise in systolic as well as diastolic BP for prolonged period:
- A. Ephedrine
- B. Epinephrine
- C. Dopamine
- D. Norepinephrine
Correct Answer: D
Rationale: Norepinephrine increases both systolic and diastolic BP with prolonged effect.
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Once phosphorylated, the intracellular segment of a receptor tyrosine kinase
- A. Activates adenylate cyclase
- B. Causes dissociation of the ligand from an allosteric binding site
- C. Terminates intracellular signaling cascades
- D. Allows docking of intracellular proteins involved in signal transduction
Correct Answer: D
Rationale: Phosphorylation enables docking of signaling proteins, initiating transduction cascades.
Patients who are beginning therapy with vitamin B12 need to be monitored for:
- A. Hypertensive crisis that may occur in the first 36 hours
- B. Hypokalemia that occurs in the first 48 hours
- C. Leukopenia that occurs at 1 to 3 weeks of therapy
- D. Thrombocytopenia that may occur at any time in therapy
Correct Answer: B
Rationale: Hypokalemia can occur early in B12 therapy as red cell production surges, shifting potassium; other effects are rare.
Which person should be treated with prophylactic antitubercular medication?
- A. A child who attends the same school with a child who has tuberculosis
- B. A nurse who is working in a hospital
- C. An individual who is HIV-positive with a negative TB skin test
- D. A patient who has close contact with someone who has tuberculosis
Correct Answer: D
Rationale: Close contact with TB warrants prophylaxis; school , hospital work , or HIV without exposure don't. Personal contact with a person having a diagnosis of tuberculosis is required to indicate prophylactic treatment with antitubercular therapy.
Sarah developed a rash after using a topical medication. This is a type __ allergic drug reaction.
- A. I
- B. II
- C. III
- D. IV
Correct Answer: D
Rationale: A rash from topical medication is a Type IV (delayed hypersensitivity) reaction , typically contact dermatitis, not immediate (I), cytotoxic (II), or immune complex (III).
Which of the following would be most important for the nurse to do to ensure the safe use of prescription drugs in the institutional setting?(Select one that does not apply.)
- A. Administering drugs
- B. Monitoring clients for drug effects
- C. Prescribing drugs
- D. Evaluating clients for toxic effects
Correct Answer: C
Rationale: In the institutional setting, the nurse's role to ensure safe use of prescription drugs includes administering drugs, monitoring drug effects, evaluating for toxic effects, and educating clients and caregivers about drugs.