ATI Pharmacology Quizlet Related

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A client is taking oral Oxycodone and Ibuprofen in recommended doses. The nurse should identify that an interaction between these two medications will cause which of the following findings?

  • A. A decrease in serum levels of ibuprofen, possibly leading to a need for increased doses of this medication.
  • B. A decrease in serum levels of oxycodone, possibly leading to a need for increased doses of this medication.
  • C. An increase in the expected therapeutic effect of both medications.
  • D. An increase in expected adverse effects for both medications.
Correct Answer: C

Rationale: When Oxycodone, a narcotic analgesic, and Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), are taken together, they work synergistically to enhance the pain-relieving effects of both medications. These drugs act through different mechanisms, leading to a combined analgesic effect that is more effective than when used alone. Therefore, the interaction between Oxycodone and Ibuprofen results in an increase in the expected therapeutic effect of both medications.