What is a common side effect that typically occurs with the initial therapy of Nitroglycerine as a result of increased vasodilation?
- A. Abdominal cramps
- B. Calf pain
- C. Headache
- D. Blurred vision
Correct Answer: C
Rationale: Headache is a common side effect associated with the initial therapy of Nitroglycerine due to its vasodilatory properties. The vasodilation caused by Nitroglycerine leads to relaxation of blood vessels, including those in the head, which can result in headaches. This side effect is considered normal and is often transient, diminishing with continued use of the medication.
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A client has a prescription for Heparin. Which of the following laboratory tests should be monitored while the client is receiving Heparin?
- A. Prothrombin time (PT)
- B. Complete blood count (CBC)
- C. International normalized ratio (INR)
- D. Activated partial thromboplastin time (aPTT)
Correct Answer: D
Rationale: Activated partial thromboplastin time (aPTT) is the correct laboratory test to monitor while a client is receiving Heparin. This test is used to assess the therapeutic levels of heparin in the blood, ensuring that the dose is within the safe and effective range. Monitoring aPTT helps healthcare providers adjust the dosage of Heparin to prevent complications such as bleeding or clotting.
A client has difficulty swallowing medications and is prescribed enteric-coated aspirin PO once daily. The client asks if the medication can be crushed to make it easier to swallow. Which of the following responses should the nurse provide?
- A. Crushing the medication might cause you to have a stomachache or indigestion.
- B. Crushing the medication is a good idea, and I can mix it in some ice cream for you.
- C. Crushing the medication would release all the medication at once, rather than over time.
- D. Crushing is unsafe, as it destroys the ingredients in the medication.
Correct Answer: A
Rationale: Crushing an enteric-coated medication can cause it to break down in the stomach instead of the intestines, potentially leading to gastrointestinal distress like stomachache or indigestion. It is important to take enteric-coated medications whole to ensure they are properly absorbed in the intestines and to prevent irritation to the stomach.
Which of the following does not describe intravenous injection.
- A. tend to produce more immediate adverse reaction.
- B. Too high concentration of the drug is readily obtained
- C. Chance of penetration into an artery instead of vein
- D. Convenient, safe , economica l
Correct Answer: D
Rationale: The statement "Convenient, safe, economical" does not accurately describe intravenous injection. Intravenous injection is generally considered to be less convenient compared to other routes of administration due to the need for proper training, sterile technique, and close monitoring during drug administration. While it can be effective in delivering drugs quickly and directly into the bloodstream, it is not always the safest or most economical option. Intravenous administration carries risks such as infection, phlebitis, and possible adverse reactions that need to be carefully monitored. Additionally, the cost of intravenous drug administration tends to be higher due to the need for specialized equipment and trained personnel.
Restoration of blood flow results through the dissolution of clot by:
- A. fibrin
- B. plasmin
- C. thrombin
- D. prothrombin
Correct Answer: B
Rationale: Plasmin is an enzyme that is responsible for breaking down fibrin, a protein that forms blood clots. When an area of vessel needs to have its blood flow restored, such as after a clot has formed, plasmin is activated to dissolve the clot. By breaking down the fibrin mesh of the clot, plasmin helps restore normal blood flow in the affected vessel. Therefore, the restoration of blood flow results through the dissolution of clot by plasmin, making option B the correct answer.
After administering the drug Atropine to a patient, the nurse notices side effects of dry mouth, tachycardia, and drowsiness. The nurse suspects ans overdose of the drug. Which of the following is the antidote for Atropine?
- A. Flumazenil
- B. Naloxone
- C. Physostigmine
- D. Protamine sulfate
Correct Answer: C
Rationale: Physostigmine is the antidote for Atropine overdose. Atropine is an anticholinergic drug that blocks the action of acetylcholine. Physostigmine works by increasing the levels of acetylcholine in the body, counteracting the effects of Atropine. It can help reverse the side effects of Atropine overdose, such as dry mouth, tachycardia, and drowsiness. Flumazenil is the antidote for benzodiazepines, Naloxone is the antidote for opioids, and Protamine sulfate is the antidote for heparin.