Fundamentals of Nursing Nursing Process Questions Related

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The physician prescribes didanosone (ddl [Videx]), 200mg PO every 12 hours, for a client with acquired immunodeficiency syndrome (AIDS) who is intolerant to zidovudine (azidothymidine ,AZT [Retrovir]). Which condition in the client’s history warrants cautious of this drug?

  • A. Peripheral neuropathy
  • B. Hypertension
  • C. Diabetes mellitus
  • D. Asthma
Correct Answer: A

Rationale: The correct answer is A: Peripheral neuropathy. Didanosine (ddl) can cause peripheral neuropathy as a side effect, which can exacerbate existing neuropathy. The client's history of peripheral neuropathy warrants caution with this drug to prevent further nerve damage.

Incorrect choices:
B: Hypertension - Didanosine is not contraindicated in hypertension.
C: Diabetes mellitus - While monitoring blood sugar levels is important, didanosine does not directly affect diabetes.
D: Asthma - Didanosine does not have a significant impact on asthma.

In summary, the client's pre-existing peripheral neuropathy makes it important to exercise caution with didanosine to avoid worsening this condition.