What is the pharmacological action of metformin?
- A. Biguanides
- B. Benzodiazepines
- C. Nitrates
- D. Digitalis glycosides
Correct Answer: A
Rationale: Metformin belongs to the class of medications known as biguanides. Biguanides work by decreasing glucose production in the liver and also improving insulin sensitivity in the muscles, helping to lower blood sugar levels in patients with type 2 diabetes. Additionally, metformin can also reduce glucose absorption in the intestines and increase glucose uptake in peripheral tissues. Its main pharmacological action is to improve glycemic control and reduce hyperglycemia in patients with diabetes.
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What is the common side effect that is normal with the initial therapy of Nitroglycerine due to increased vasodilation?
- A. Abdominal cramps
- B. Calf
- C. Headache
- D. Blurred vision
Correct Answer: C
Rationale: The most common side effect that is normal with the initial therapy of Nitroglycerine due to increased vasodilation is a headache. Nitroglycerine causes vasodilation of blood vessels, including the blood vessels in the head and brain. This can lead to headaches as a result of the increased blood flow and changes in blood vessel diameter. Headaches caused by Nitroglycerine are usually mild and transient. It is important to monitor patients for this expected side effect and educate them about it to ensure compliance with the medication regimen.
The nurse notes in the patient™s medication orders that the patient will be taking ibutilide (Corvert). Based on this finding, the nurse interprets that the patient has which disorder?
- A. Ventricular ectopy
- B. Atrial fibrillation
- C. Supraventricular tachycardia
- D. Bradycardia
Correct Answer: B
Rationale: Ibutilide (Corvert) is a medication commonly used to treat atrial fibrillation, a type of irregular heart rhythm that originates in the heart's upper chambers (atria). It works by restoring normal heart rhythm in patients with atrial fibrillation. Therefore, the nurse notes the use of ibutilide in the patient's medication orders, indicating that the patient has atrial fibrillation.
Reye's syndrome, a potentially fatal illness associated with liver failure and encephalopathy is associated with the administration of which over-the-counter (OTC) medication?
- A. acetaminophen (Tylenol)
- B. ibuprofen (Motrin)
- C. aspirin
- D. brompheniramine/pseudoephedrine (Dimetapp)
Correct Answer: C
Rationale: Reye's syndrome is linked to the use of aspirin in children and adolescents, particularly during viral infections. It causes severe liver and brain damage. Acetaminophen, ibuprofen, and antihistamines are not associated with this condition. Avoiding aspirin in pediatric patients is critical to prevent this rare but life-threatening syndrome.
A patient requires a nonopioid medication. The nurse knows that which medication will cause the least gastrointestinal distress?
- A. Aspirin
- B. Ketorolac
- C. Celecoxib
- D. Ibuprofen
Correct Answer: C
Rationale: Celecoxib is a selective COX-2 inhibitor, which means it primarily targets the COX-2 enzyme involved in inflammation and pain while sparing the COX-1 enzyme that protects the stomach lining. This selectivity reduces the risk of gastrointestinal distress, such as ulcers and bleeding, compared to non-selective NSAIDs like aspirin, ketorolac, and ibuprofen. Therefore, celecoxib is the best choice for patients who require a nonopioid medication with minimal gastrointestinal side effects. Nurses should consider this when selecting pain management options for patients with a history of gastrointestinal issues.
Alcoholic or hydroalcoholic solution of volatile substances
- A. decoction
- B. fluid extract
- C. solution
- D. spirits
Correct Answer: D
Rationale: A spirit is an alcoholic or hydroalcoholic solution of volatile substances obtained by distillation. It is commonly used in the production of alcoholic beverages and in the pharmaceutical industry for preparing tinctures and extracts. Spirits are characterized by their high alcohol content and ability to extract and preserve the properties of the substances they are derived from. Decoction is a method of extracting compounds from plants using boiling water, fluid extract is a concentrated liquid extract of a substance, solution refers to a homogeneous mixture of substances, and syrup is a thick, sweet liquid usually made by dissolving sugar in water.