A 2-year-old child is being treated for lead poisoning. Which of the following findings indicates the need for further intervention?
- A. Increased urine output
- B. Decreased hemoglobin levels
- C. Weight gain
- D. Improved developmental milestones
Correct Answer: B
Rationale: Lead poisoning can cause anemia, so a decrease in hemoglobin levels would indicate that further intervention is necessary.
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The nurse is preparing to administer a dose of digoxin (Lanoxin) to a child in heart failure (HF). Which is a beneficial effect of administering digoxin (Lanoxin)?
- A. It decreases edema.
- B. It decreases cardiac output.
- C. It increases heart size.
- D. It increases venous pressure.
Correct Answer: A
Rationale: Digoxin has a rapid onset and is useful for increasing cardiac output, decreasing venous pressure, and, as a result, decreasing edema. Cardiac output is increased by digoxin. Heart size and venous pressure are decreased by digoxin.
Recurrent Neisserial meningitis in children is suggestive of deficiency of ----- complement.
- A. C3
- B. C4
- C. C8
- D. All
Correct Answer: C
Rationale: Recurrent Neisserial meningitis is suggestive of a deficiency in the terminal complement components, particularly C8, which is crucial for bacterial lysis.
FISH is helpful in diagnosing:
- A. Prader-Willi syndrome
- B. Di George syndrome
- C. Klinefelter's syndrome
- D. Turner's syndrome
Correct Answer: B
Rationale: FISH (Fluorescence In Situ Hybridization) is particularly useful in diagnosing DiGeorge syndrome, which involves microdeletions on chromosome 22.
Anthracycline (doxorubicin) on rare occasion causes acute inflammatory myocardial injury, but more classically results in dilated cardiomyopathy (DCM) in up to 30% of patients with a cumulative dose of doxorubicin exceeding
- A. 250 mg/m²
- B. 350 mg/m²
- C. 450 mg/m²
- D. 550 mg/m²
Correct Answer: D
Rationale: A cumulative dose of doxorubicin exceeding 550 mg/m² is associated with increased risk of dilated cardiomyopathy.
Duchenne muscular dystrophy:
- A. Has an association with malignant hyperpyrexia
- B. Is a reason for never running properly
- C. Is better diagnosed with muscle biopsy than gene probe
- D. Is associated with speech delay
Correct Answer: D
Rationale: Duchenne muscular dystrophy is associated with speech delay due to progressive muscle weakness, including facial muscles affecting speech.