Medical Surgical NCLEX RN Related

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A 28-year-old client with cancer is afraid of experiencing a febrile reaction associated with blood transfusions. He asks the nurse if this will happen to him. The nurse's best response is which of the following?

  • A. Febrile reactions are caused when antibodies on the surface of blood cells in the transfusion are directed against antigens of the recipient.
  • B. Febrile reactions can usually be prevented by administering antipyretics and antihistamines before the start of the transfusion.
  • C. Febrile reactions are rarely immune-mediated and can be a sign of hemolytic transfusion.
  • D. Febrile reactions primarily occur within 15 minutes after initiation of the transfusion and can occur during the blood transfusion.
Correct Answer: B

Rationale: Febrile reactions can often be prevented with premedication like antipyretics and antihistamines, which is a reassuring and accurate response for the client.