A 5-year-old boy has systemic juvenile idiopathic arthritis (sJIA) with systemic manifestations including fever, hepatosplenomegaly, and pericarditis. Of the following, the BEST initial treatment for this boy is
- A. NSAIDs
- B. systemic glucocorticoids
- C. TNF-a inhibitors
- D. IL-1 antagonists
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
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Which of the following is NOT a potential complication of neonatal jaundice?
- A. kernicterus
- B. deafness
- C. cerebral palsy
- D. cardiomyopathy
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Physiologic jaundice in a newborn can be caused by:
- A. fetal-maternal blood incompatibility.
- B. destruction of red blood cells as a result of antibody reaction.
- C. liver's inability to bind bilirubin adequately for excretion.
- D. immature kidneys' inability to hydrolyze and excrete bilirubin.
Correct Answer: C
Rationale: Physiologic jaundice in a newborn, also known as neonatal jaundice, is a common condition in newborns characterized by yellow discoloration of the skin and eyes due to elevated levels of bilirubin in the blood. In newborns, the liver is not fully developed, leading to an inability to efficiently process and excrete bilirubin. Bilirubin is a byproduct of the breakdown of red blood cells, and in newborns, the liver may not yet be able to efficiently bind bilirubin for excretion, leading to its accumulation in the blood and manifesting as jaundice. Physiologic jaundice typically occurs around 2 to 4 days after birth and usually resolves on its own without treatment as the baby's liver matures and becomes more efficient at processing bilirubin.
The therapeutic effect of phototherapy depends on the following factors EXCEPT
- A. distance between the lights and the infant
- B. skin color
- C. surface area of exposed skin
- D. in vivo metabolism and excretion of bilirubin
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Which would be the best play activity for a 6-month-old infant to provide tactile stimulation?
- A. Allow to splash in bath.
- B. Give various colored blocks.
- C. Play music box, tapes, or CDs.
- D. Use infant swing or stroller.
Correct Answer: A
Rationale: Allowing the 6-month-old infant to splash in the bath would provide tactile stimulation as they explore the sensation of water on their skin. Water play can be a fun and engaging way to engage the sense of touch, helping the infant develop sensory awareness. The feeling of water on their hands and body can provide a different sensory experience compared to other play activities. Additionally, the gentle splashing can also help with the development of hand-eye coordination as the infant reaches out to touch and interact with the water.
Centers for Disease Control and Prevention (CDC) recommend the blood lead level that may cause learning problems is
- A. 1 to 5¼g/dL
- B. 5 to 10 μg/dL
- C. 10 to 15¼g/dL
- D. 15 to 20¼g/dL
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.