Nokea
A 57-year-old man was recently diagnosed with Type-2 diabetes mellitus and placed on a medication. He began having myalgias and feeling sick and later developed respiratory distress, so he went to the hospital. His pH was 7.2, and he had elevated blood lactate levels. Which drug is likely causing his problem?
- A. Acarbose
- B. Glyburide
- C. Metformin
- D. Pioglitazone
Correct Answer: C
Rationale: Metformin is associated with lactic acidosis, presenting with low pH and high lactate, especially in overdose or renal impairment.
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A 35-year-old male patient is admitted to the hospital with pneumonia. He was originally being treated at home, but became worse when he quit taking his medicine. What would be an appropriate nursing diagnosis for this patient?
- A. Deficient knowledge: monitoring temperature
- B. Noncompliance
- C. Risk for injury related to office visits
- D. Non-adherence: overuse
Correct Answer: B
Rationale: Noncompliance reflects the patient's failure to continue prescribed treatment, worsening his condition.
Release of the mineralcorticoids is stimulated with:
- A. Low concentration of \mathrm{Na}+ in the blood
- B. Hypokalemia
- C. Low concentration of angiotensin II in the blood
- D. Low concentration of \mathrm{Mg} 2+ in the blood
Correct Answer: A
Rationale: Low blood sodium stimulates aldosterone release via the renin-angiotensin system.
The U.S. Food and Drug Administration MedWatch system is activated when:
- A. There is an adverse event to a vaccine.
- B. The patient has a severe reaction that is noted in the 'Severe Reaction' section in the medication label.
- C. A lactating woman takes a medication that is potentially toxic to the breastfeeding infant.
- D. An adverse event or serious problem occurs with a medication that is not already identified on the label.
Correct Answer: D
Rationale: MedWatch reports new, unlabeled adverse events , beyond vaccines , known reactions , or lactation risks .
Which of the following is a contraindication of glucocorticoid use?
- A. Psychosis
- B. Allergic dermatitis
- C. Autoimmune hemolytic anemia
- D. Angioneurotic edema
Correct Answer: A
Rationale: Glucocorticoids can exacerbate psychosis, making it a contraindication, unlike the other conditions which they can treat.
Following are the true receptors, except one
- A. Beta adrenergic receptors
- B. Na-K-ATP ase
- C. Phosphodiesterase
- D. Plasma proteins
Correct Answer: D
Rationale: Plasma proteins bind drugs but are not receptors.