Microbiology An Introduction Tortora Test Bank Related

Review Microbiology An Introduction Tortora Test Bank related questions and content

A child entering the school for the first time was given Mantoux test in order to determine if there was a need for revaccination. The reaction was negative. What is the meaning of this test result?

  • A. No cell-mediated immunity to tuberculosis
  • B. Availability of cell-mediated immunity to tuberculosis
  • C. No antibodies to the tuberculosis bacteria
  • D. No anti-toxic immunity to tuberculosis
Correct Answer: B

Rationale: The correct answer is B: Availability of cell-mediated immunity to tuberculosis. A negative Mantoux test indicates the presence of an immune response to the TB bacteria, as the test measures the body's delayed hypersensitivity reaction to TB antigens. This means the child has been exposed to TB in the past or has been vaccinated, resulting in the development of cell-mediated immunity against TB.

Incorrect choices:
A: No cell-mediated immunity to tuberculosis - This is incorrect as a negative Mantoux test actually indicates the presence of cell-mediated immunity.
C: No antibodies to the tuberculosis bacteria - Mantoux test measures cell-mediated immunity, not antibody response.
D: No anti-toxic immunity to tuberculosis - Mantoux test does not assess anti-toxic immunity, it specifically measures cell-mediated immunity.