Nokea
A child is undergoing remission induction therapy to treat leukemia. Allopurinol is included in the regimen. The main reason for administering allopurinol as part of the client’s chemotherapy regimen is to:
- A. Prevent metabolic breakdown of xanthine to uric acid
- B. Prevent uric acid from precipitating in the ureters
- C. Enhance the production of uric acid to ensure adequate excretion of urine
- D. Ensure that the chemotherapy doesn’t adversely affect the bone marrow
Correct Answer: A
Rationale: Allopurinol prevents the breakdown of xanthine to uric acid, reducing the risk of uric acid nephropathy during chemotherapy-induced tumor lysis.
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The jugular venous pressure (JVP) has a predictable relationship with pulmonary artery wedge pressure (PAWP). A JVP of >12 mm Hg predicted PAWP >22 mm Hg by 88% in which of the following trials?
- A. BNP
- B. ESCAPE
- C. EVEREST
- D. EMPA REG
Correct Answer: B
Rationale: The ESCAPE trial studied the effectiveness of therapies in patients with advanced heart failure and showed that elevated JVP was correlated with high pulmonary artery wedge pressures.
The nurse is teaching the importance of an exercise regime that includes walking daily for a group of clients with asthma, chronic bronchitis, and emphysema at a pulmonary rehabilitation clinic. Which rationale should the nurse include when motivating the clients?
- A. Daily exercise and walking enhances cardiovascular fitness
- B. Exercise eliminates the need for bronchodilator medications.
- C. Walking daily reverses lung damage caused by chronic conditions.
- D. Physical activity increases mucus production to clear airways.
Correct Answer: A
Rationale: Regular exercise improves cardiovascular fitness, which can enhance overall respiratory function and quality of life in clients with chronic pulmonary conditions.
Commonly used anti-epileptic drugs in children include:
- A. Sodium valproate
- B. Lamotrigine
- C. Topiramate
- D. Phenytoin
Correct Answer: A
Rationale: The correct answer is A because sodium valproate is a commonly used anti-epileptic drug in children. The other options (b-e) are also used but are not the most common first-line treatment.
Recognised features of brucellosis include:
- A. Osteomyelitis
- B. Liver granuloma
- C. Pericarditis
- D. Splenomegaly
Correct Answer: D
Rationale: Splenomegaly
The MOST common cyanotic congenital cardiac lesion to present in the newborn period is
- A. dextroposed heart
- B. transposition of great arteries
- C. tetralogy of Fallot
- D. truncus arteriosus
Correct Answer: B
Rationale: Transposition of the great arteries is the most common cyanotic congenital heart defect presenting in the neonatal period.