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A child who weighs 66 pounds receives a prescription for amoxicillin 80 mg/kg/day by mouth in divided doses every 12 hours. The bottle is labeled, 'Amoxicillin for Oral Suspension, USP 400 mg per 5 mL.' How many mL should the nurse administer with each dose? (Enter numerical value only.)
Correct Answer: 15
Rationale: Weight: 66 / 2.2 = 30 kg. Daily dose: 80 mg/kg/day × 30 = 2400 mg/day. Per dose (every 12 hours): 2400 / 2 = 1200 mg. Volume: (1200 × 5) / 400 = 15 mL.
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A client scheduled for coronary artery bypass surgery is to receive an intravenous infusion of 1 gram cefazolin in 50 mL 0.9% Sodium Chloride, USP over 30 minutes. The nurse should program the infusion pump to deliver how many mL/hour? (Enter numeric value only, as a whole number.)
Correct Answer: 100
Rationale: Infusion rate = Volume / Time. Volume is 50 mL, time is 30 minutes = 0.5 hours. So, 50 / 0.5 = 100 mL/hour.
Penicillin G procaine 240,000 units Intramuscularly is prescribed for a 4-year-old child who has a streptococcal respiratory Infection. The medication vial is labeled 1,200,000 units/2 mL. How many ml. should the nurse administer? (Enter numeric value only. If rounding is required, round to the nearest tenth.)
Correct Answer: 0.4
Rationale: Concentration: 1,200,000 units / 2 mL = 600,000 units/mL. Volume = 240,000 / 600,000 = 0.4 mL.
A client receives a prescription for amoxicillin 2 g/clavulanate 125 mg by mouth every 12 hours for 10 days. The medication is available in 1000 mg/62.5 mg extended release tablets. How many tablets should the nurse administer? (Enter numerical value only.)
Correct Answer: 2
Rationale: Total dose = 2000 mg amoxicillin + 125 mg clavulanate. Tablet strength = 1000 mg/62.5 mg. Tablets = (2000 + 125) / (1000 + 62.5) = 2 tablets.
The healthcare provider prescribes streptomycin 200 mg intramuscularly every 12 hours. The vial is labeled, 'Streptomycin 1 gram/2.5 mL. How many milliliters should the nurse administer? (Enter numerical value only. (If rounding is required, round to the nearest tenth.))
Correct Answer: 0.5
Rationale: Concentration: 1 g = 1000 mg / 2.5 mL. Proportion: 1000 mg / 2.5 mL = 200 mg / x mL. Solving, x = (200 × 2.5) / 1000 = 0.5 mL.
A client who weighs 91 kg receives a prescription for a continuous infusion of dopamine at 3 mcg/kg/min. The solution is labeled, 'Dopamine 400 mg in 5% Dextrose Injection 250 mL.' How many mL/hr should the nurse program the infusion pump to deliver? (Enter numeric value only. If rounding is required, round to the nearest tenth.)
Correct Answer: 10.2
Rationale: Calculate dose: 3 mcg/kg/min × 91 kg = 273 mcg/min. Convert to hourly: 273 × 60 = 16380 mcg/hour. Concentration: 400 mg = 400000 mcg in 250 mL = 1600 mcg/mL. Infusion rate = 16380 / 1600 = 10.2375 mL/hour, rounded to 10.2.