NCLEX Trainer Test 1 Related

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A client is admitted to the hospital with findings of liver failure with ascites. The health care provider orders spironolactone (Aldactone). What is the pharmacological effect of this medication?

  • A. Promotes sodium and chloride excretion
  • B. Increases aldosterone levels
  • C. Depletes potassium reserves
  • D. Combines safely with antihypertensives
Correct Answer: A

Rationale: Spironolactone promotes sodium and chloride excretion while sparing potassium and decreasing aldosterone levels. It has no effect on ammonia levels.