A client is experiencing an overdosage of heparin. The nurse would expect to administer which of the following?
- A. Vitamin K1
- B. Protamine
- C. Ticlopidine
- D. Tenecteplase
Correct Answer: B
Rationale: Heparin overdosage is treated with protamine, which neutralizes heparin's anticoagulant effects.
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A client is being discharged from the hospital with a prescription for clopidogrel. The nurse would instruct the client about which of the following as a possible adverse reaction? Select all that apply.
- A. Skin rash
- B. Bleeding
- C. Heart palpitations
- D. Nausea
- E. Constipation
Correct Answer: A,B,C,E
Rationale: The most common adverse reactions associated with clopidogrel are skin rash, dizziness, bleeding, palpitations, and constipation.
A client with thrombotic stroke is administered ticlopidine. The nurse would assess the client for which of the following?
- A. Dyspepsia
- B. Dyspnea
- C. Hematoma
- D. Bradycardia
Correct Answer: A
Rationale: The nurse should monitor for dyspepsia in the client who has been administered ticlopidine. Hematoma is an adverse reaction to heparin. Dyspnea is an adverse reaction to protamine sulfate and treprostinil. Bradycardia is an adverse reaction to protamine sulfate.
Protamine is used to treat overdose of which of the following medications? Select all that apply.
- A. Clopidogrel (Plavix)
- B. Heparin
- C. Enoxaparin (Lovenox)
- D. Alreplase (Activase)
- E. Warfarin (Coumadin)
Correct Answer: B,C
Rationale: Protamine is used to treat overdose of heparin and low-molecular-weight heparins (LMWHs).
When reviewing the medical records of several clients, the nurse understands that the use of anticoagulants is contraindicated in clients with which of the following medical conditions? Select all that apply.
- A. Leukemia
- B. Hypotension
- C. Atrial fibrillation
- D. GI ulcers
- E. Tuberculosis
Correct Answer: A,D,E
Rationale: Anticoagulants are contraindicated in clients with known sensitivity to the drug, active bleeding, hemorrhagic disease, tuberculosis, leukemia, uncontrolled hypertension, GI ulcers, recent eye or CNS surgery, aneurysms, and severe renal and hepatic disease and during pregnancy and lactation.
After teaching a group of nursing students about heparins, the instructor determines that the teaching was successful when the students identify which of the following as an example of a low-molecular-weight heparin (LMWH)? Select all that apply.
- A. Dalteparin
- B. Streptokinase
- C. Enoxaparin
- D. Warfarin
- E. Tinzaparin
Correct Answer: A,C,E
Rationale: Dalteparin, enoxaparin, and tinzaparin are all examples of LMWHs. Streptokinase is a thrombolytic; warfarin is an oral anticoagulant.
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