Pharmacology and the Nursing Process 9th Edition Test Bank Related

Review Pharmacology and the Nursing Process 9th Edition Test Bank related questions and content

. A client is prescribed prednisone (Deltasone) daily. Which statement best explains why the nurse should instruct the client to take this drug in the morning?

  • A. Taking the drug at the same time every day establishes a regular routine, reducing the risk of forgetting a dose.
  • B. Prednisone has a longer half-life with morning administration, making it more effective.
  • C. Morning administration of prednisone mimics the body’s natural corticosteroid secretion pattern.
  • D. Prednisone is best absorbed when taken on an empty stomach first thing in the morning.
Correct Answer: C

Rationale: The correct answer is C because morning administration of prednisone mimics the body's natural corticosteroid secretion pattern. Cortisol, a natural corticosteroid, is typically highest in the morning and decreases throughout the day. By taking prednisone in the morning, the client aligns the drug's peak concentration with the body's natural cortisol levels, optimizing its therapeutic effects.

Choice A is incorrect because while taking the drug at the same time daily is important for consistency, it does not specifically address the rationale for morning administration. Choice B is incorrect as the effectiveness of prednisone is not solely dependent on its half-life but also on alignment with the body's natural rhythm. Choice D is also incorrect as prednisone can be taken with food and does not necessarily require an empty stomach for optimal absorption.