A client is prescribed sargramostim (Leukine). Before administering the drug, the nurse would inform the client that which of the following may occur with this drug? Select all that apply.
- A. Bone pain
- B. Anemia
- C. Infection
- D. Nausea
- E. Rash
Correct Answer: A,D,E
Rationale: Headache, bone pain, nausea, vomiting, diarrhea, alopecia, and rash are adverse reactions the nurse should inform the client about prior to the administration of sargramostim (Leukine).
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A client with iron deficiency anemia is prescribed iron supplements. After administering the drug, the nurse would assess the client for which of the following as a possible adverse reaction related to gastrointestinal function?
- A. Headache
- B. Darker stools
- C. Soreness
- D. Backache
Correct Answer: B
Rationale: The nurse needs to closely monitor the client for darker stools as an adverse gastrointestinal reaction to iron supplements. Headache and backache are the generalized system reactions to iron supplements. Soreness is a generalized system reaction to the administration of iron when given though the parenteral route.
Based on the nurse's understanding of epoetin alfa, the nurse would expect to administer the drug cautiously to a client with a history of which of the following? Select all that apply.
- A. Diabetes
- B. Renal failure
- C. History of seizures
- D. Congestive heart failure
- E. Hypotension
Correct Answer: C,D
Rationale: Epoetin alfa (Procrit) is used cautiously in clients with hypertension, heart disease, congestive heart failure, or a history of seizures.
A client with chronic kidney disease is prescribed epoetin alfa (Procrit). Which of the following would be appropriate for the nurse to do when administering this drug to promote optimal response? Select all that apply.
- A. Shake the vial vigorously prior to administration.
- B. Use the vial for multiple doses.
- C. Discard any unused portion after administration.
- D. Administer the drug either intravenously or subcutaneously.
- E. Avoid using the drug if the client is receiving dialysis.
Correct Answer: C,D
Rationale: When administering epoetin alfa (Procrit) to a client with chronic kidney disease, the following apply: the drug is given three times weekly IV or subcutaneously, if the client is receiving dialysis, the drug is administered into the venous access line, the drug is mixed gently during preparation for administration; shaking may denature the glycoprotein; and the vial is used for only one dose and any remaining or unused portion is discarded.
A client is to receive oprelvekin (Neumega). After administering the drug, the nurse would be alert for which of the following as a possible adverse reaction? Select all that apply.
- A. Bone pain
- B. Fluid retention
- C. Syncope
- D. Nausea
- E. Fever
Correct Answer: B,C,E
Rationale: Fluid retention, peripheral edema, dyspnea, syncope, fever, and allergic reactions are adverse reactions associated with the administration of oprelvekin (Neumega).
A nurse is caring for a client who has been prescribed iron dextran. The nurse understands that which information is used to calculate the drug dosage?
- A. Client's age
- B. Client's height
- C. Hemoglobin level
- D. Platelet count
Correct Answer: C
Rationale: Hemoglobin level and body weight of the client are important information the nurse requires to calculate the drug dosage for administering iron dextran. The client's age, height, and platelet count are not essential information when calculating drug dosage for iron dextran.
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