RN NCLEX Practice Test Related

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A client is taking Deltasone (prednisone) each morning to treat his systemic lupus erythematosus. Which statement best explains the reason for taking the prednisone in the morning?

  • A. There is less chance of forgetting the medication if taken in the morning.
  • B. There will be less fluid retention if taken in the morning.
  • C. The medication is absorbed best with the breakfast meal.
  • D. Morning administration mimics the body's natural secretion of corticosteroid.
Correct Answer: D

Rationale: Prednisone is taken in the morning to mimic the body’s natural cortisol peak, which occurs early in the day, minimizing adrenal suppression and side effects. Timing does not primarily affect forgetting, fluid retention, or absorption.