NCLEX RN Client Needs Physiologic Adaptation Related

Review NCLEX RN Client Needs Physiologic Adaptation related questions and content

A client prescribed prazosin hydrochloride asks the nurse why the first dose must be taken at bedtime. Which response by the nurse is based on the understanding of the first dose use of prazosin hydrochloride?

  • A. Treatment with prazosin hydrochloride results in drowsiness.
  • B. Treatment with prazosin hydrochloride can cause dependent edema.
  • C. Prazosin hydrochloride should be taken when the stomach is empty.
  • D. Treatment with prazosin hydrochloride can cause dizziness or possible syncope.
Correct Answer: D

Rationale: Prazosin is an alpha-adrenergic blocking agent. 'First-dose hypotensive reaction' may occur during early therapy, which is characterized by dizziness, lightheadedness, and possible loss of consciousness. The occurrence of these effects is better tolerated if the client is in bed. This also can occur when the dosage is increased. This effect usually disappears with continued use or the dosage is decreased.