Assessment of High Risk Pregnancy NCLEX Questions Related

Review Assessment of High Risk Pregnancy NCLEX Questions related questions and content

Which analysis of maternal serum is the best predictor of chromosomal abnormalities in the fetus?

  • A. Biophysical profile
  • B. Multiple-marker screening
  • C. Lecithin-to-sphingomyelin ratio
  • D. Blood type and crossmatch of maternal and fetal serum
Correct Answer: B

Rationale: The correct answer is B: Multiple-marker screening. This analysis measures levels of certain proteins and hormones in maternal serum to assess the risk of chromosomal abnormalities in the fetus. It is considered the best predictor because abnormal levels of these markers can indicate conditions like Down syndrome. Biophysical profile (A) assesses fetal well-being but does not directly predict chromosomal abnormalities. Lecithin-to-sphingomyelin ratio (C) is used to assess fetal lung maturity, not chromosomal abnormalities. Blood type and crossmatch (D) are important for identifying Rh incompatibility but do not predict chromosomal abnormalities.