Free NCLEX RN Exam Related

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A client who has been receiving Urokinase (UPA) for deep vein thrombosis is noted to have dark brown urine in the urine collection bag. Which action should the nurse take immediately?

  • A. Prepare an injection of vitamin K
  • B. Irrigate the urinary catheter with 50 mL of normal saline
  • C. Offer the client additional oral fluids
  • D. Withhold the medication and notify the physician
Correct Answer: D

Rationale: Dark brown urine may indicate hematuria, a potential side effect of Urokinase, a thrombolytic agent. The nurse should withhold the medication and notify the physician immediately to assess for bleeding complications. Vitamin K is used for warfarin reversal, irrigation is inappropriate, and fluids won’t address the issue.