Roach's Introductory Clinical Pharmacology 11th Edition - Thyroid and Antithyroid Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Thyroid and Antithyroid Drugs related questions and content

A client with a heart condition controlled on which of the following drugs must be monitored closely by the nurse for worsening atrial fibrillation if levothyroxine is initiated to treat hypothyroidism? Select all that apply.

  • A. Lisinopril (Prinivil)
  • B. Digoxin (Lanoxin)
  • C. Diltiazem (Cardizem)
  • D. Metoprolol (Toprol)
  • E. Warfarin (Coumadin)
Correct Answer: B,D

Rationale: A client with a heart condition controlled on digoxin (Lanoxin) and metoprolol (Toprol) must be monitored closely by the nurse for worsening atrial fibrillation if levothyroxine is initiated to treat hypothyroidism because levothyroxine can decrease the effectiveness of digoxin and beta blockers (metoprolol).