RN Medical Surgical Hesi Exam Related

Review RN Medical Surgical Hesi Exam related questions and content

A client with acquired immune deficiency syndrome (AIDS) and Pneumocystis jiroveci pneumonia has a CD4+ T cell count of 200 cells/mm³ (20%). The client asks the nurse why they have these recurring massive infections. Which pathophysiologic mechanism should the nurse describe in response to this client's question?

  • A. The humoral immune response lacks B cells that form antibodies and opportunistic infections result.
  • B. Inadequate numbers of T lymphocytes are available to initiate cellular immunity and macrophages.
  • C. Bone marrow suppression of white blood cells causes insufficient cells to phagocytize organisms.
  • D. Exposure to multiple environmental infectious agents overburdens the immune system until it fails.
Correct Answer: B

Rationale: Inadequate numbers of CD4+ T cells, due to HIV infection, impair cellular immunity, leading to susceptibility to opportunistic infections like Pneumocystis jiroveci pneumonia.