Psychiatric Nursing: Contemporary Practice 6th Edition - Bipolar Disorders: Management of Mood Lability Related

Review Psychiatric Nursing: Contemporary Practice 6th Edition - Bipolar Disorders: Management of Mood Lability related questions and content

A client with bipolar disorder is receiving divalproex sodium as part of the treatment plan. When monitoring the client?s blood level for this drug, which level would alert the nurse to the need to change the dosage?

  • A. 30 ng/mL
  • B. 55 ng/mL
  • C. 75 ng/mL
  • D. 115 ng/mL
Correct Answer: D

Rationale: The therapeutic range for divalproex sodium (valproic acid) is 50?100 µg/mL (often reported as ng/mL in some contexts). A level of 115 ng/mL (D) is above this range, indicating potential toxicity and the need for dosage reduction. Levels of 30, 55, and 75 ng/mL (A, B, C) are below or within the therapeutic range.