A client with chronic kidney disease is prescribed epoetin alfa (Procrit). Which of the following would be appropriate for the nurse to do when administering this drug to promote optimal response? Select all that apply.
- A. Shake the vial vigorously prior to administration.
- B. Use the vial for multiple doses.
- C. Discard any unused portion after administration.
- D. Administer the drug either intravenously or subcutaneously.
- E. Avoid using the drug if the client is receiving dialysis.
Correct Answer: C,D
Rationale: When administering epoetin alfa (Procrit) to a client with chronic kidney disease, the following apply: the drug is given three times weekly IV or subcutaneously, if the client is receiving dialysis, the drug is administered into the venous access line, the drug is mixed gently during preparation for administration; shaking may denature the glycoprotein; and the vial is used for only one dose and any remaining or unused portion is discarded.
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A client is prescribed ferrous sulfate. Before administering the drug, the nurse reviews the client's medical record. The nurse would withhold the drug and contact the primary health care provider if the client's history revealed which of the following? Select all that apply.
- A. Hemolytic anemia
- B. Vitamin B12 deficiency anemia
- C. Anemia of chronic kidney disease
- D. Hemochromatosis
- E. Hypertension
Correct Answer: A,D
Rationale: The use of iron supplements is contraindicated in clients with hemochromatosis or hemolytic anemia.
A client with megaloblastic anemia is prescribed leucovorin. The nurse would identify which of the following as a contraindication for this drug?
- A. Pernicious anemia
- B. Hemochromatosis
- C. Uncontrolled hypertension
- D. Hypersensitivity to human albumin
Correct Answer: A
Rationale: Leucovorin is contraindicated in clients with pernicious anemia or other anemias in which vitamin B12 is deficient. Leucovorin is not contraindicated in clients with hemochromatosis, uncontrolled hypertension, and hypersensitivity to human albumin. Epoetin alfa is contraindicated in clients with uncontrolled hypertension and hypersensitivity to human albumin. Iron compounds are contraindicated in clients with hemochromatosis or hemolytic anemia.
A nurse is caring for a client with iron deficiency anemia who is receiving iron supplements. What information should the nurse include in the teaching plan for this client?
- A. Frequency of urination will increase.
- B. Soreness of throat might occur.
- C. Itching of throat might occur.
- D. Color of stools will become darker.
Correct Answer: D
Rationale: The nurse should inform the client receiving oral iron supplements that the color of stools will become darker. Frequency of urination is not known to increase with the oral administration of iron supplements. Similarly, soreness of the throat and itching of the throat are also not known to occur with the oral administration of iron supplements.
A client is prescribed ferrous sulfate (Feosol). Which of the following adverse reactions should the nurse discuss with a client prior to the administration of this drug? Select all that apply.
- A. Constipation
- B. Fluid retention
- C. Nausea
- D. Fatigue
- E. Dark stools
Correct Answer: A,C,E
Rationale: GI irritation, nausea, vomiting, constipation, diarrhea, darker stools, headache, backache, and allergic reactions are adverse reactions the nurse should discuss with a client prior to the administration of ferrous sulfate (Feosol).
A nurse is caring for a client with hypertension who is prescribed epoetin alfa for anemia. Which of the following would the nurse include in the plan of care when administering this drug to the client?
- A. Report 10 mm Hg rise in systolic blood pressure to primary health care provider.
- B. Note the hematocrit value before each dose during therapy.
- C. Shake the drug well before it is administered to the client.
- D. Administer the drug once every 3 weeks through IV route.
Correct Answer: B
Rationale: When caring for a client who is prescribed epoetin alfa, the nurse should measure the hematocrit before each dose during the drug therapy. The nurse should monitor the blood pressure of a client with hypertension when he is receiving epoetin alfa and report any rise of 20 mm Hg or more in the systolic or diastolic pressure to the primary health care provider. The drug is given three times weekly IV or SC. If the client is receiving dialysis, the drug is administered into the venous access line. The drug is mixed gently during preparation for administration. Shaking may denature the glycoprotein.
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