A client with estrogen excess may report which of the following symptoms to the nurse during ongoing assessment during treatment with Ortho-Novum 7/7/7? Select all that apply.
- A. Nausea
- B. Early breakthrough bleeding
- C. Cervical mucorrhea
- D. Edema
- E. Increased spotting
Correct Answer: A,C,D
Rationale: Signs of excess estrogen include nausea, bloating, cervical mucorrhea, polyposis, hypertension, migraine headache, breast fullness or tenderness, and edema.
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An 80-year-old client with chronic renal insufficiency is prescribed anabolic steroid therapy for the management of anemia associated with renal insufficiency. The nurse understands that this client is at increased risk for which of the following?
- A. Hypoglycemic attacks
- B. Serious cardiac disease
- C. Hypotensive shock
- D. Cancer of the prostate
Correct Answer: D
Rationale: Elderly clients undergoing anabolic steroid therapy are at an increased risk of developing cancer of the prostate gland. Therefore, anabolic steroid therapy needs to be administered cautiously in these clients. Hypoglycemic attacks, serious cardiac disease, and hypotensive shock are not seen in elderly clients on anabolic steroid therapy.
A female client receiving fluoxymesterone for metastatic breast cancer is disturbed by the physical changes seen in her body. The nurse provides support to the client based on assessment of which of the following features the client is experiencing related to this therapy?
- A. Deepening of the voice
- B. Hypopigmentation of the skin
- C. Decrease in clitoris size
- D. Increase in body weight
Correct Answer: A
Rationale: Deepening of the voice may be seen as a feature of virilization following male hormone therapy in a female client. Virilization is the acquisition of male characteristics in the female. Other features of virilization include pigmentation, and not hypopigmentation, of the skin and an increase, not a decrease, in the size of the clitoris. An increase in body weight is not a sign of virilization. It may occur due to impaired nutrition of the body.
A nurse is caring for a client receiving norethindrone for endometriosis. After administering the drug, the nurse would assess the client for which of the following? Select all that apply.
- A. Breast tenderness
- B. Edema
- C. Somnolence
- D. Hyperglycemia
- E. Thinning hair
Correct Answer: A,B
Rationale: Adverse reactions associated with norethindrone, a progestin, include breast tenderness, edema, insomnia, breakthrough bleeding, weight changes, and acne. Hyperglycemia and thinning hair are not associated with norethindrone.
A nurse should advise a client beginning therapy with testosterone (Androderm) about which of the following adverse effects? Select all that apply.
- A. Impotence
- B. Fluid retention
- C. Male-pattern baldness
- D. Somnolence
- E. Mania
Correct Answer: A,B,C
Rationale: A nurse should advise a client beginning therapy with testosterone (Androderm) of the following adverse effects: gynecomastia, testicular atrophy, inhibition of testicular function, impotence, enlargement of the penis, nausea, vomiting, jaundice, headache, anxiety, male-pattern baldness, acne, depression, and fluid and electrolyte imbalances (which include sodium, water, chloride, potassium, calcium, and phosphate retention).
When caring for a client receiving estrogen replacement therapy for postmenopausal symptoms, the nurse documents a diagnosis of Ineffective Tissue Perfusion. Which of the following conditions is the nurse referring to in the diagnosis?
- A. Thromboembolism
- B. Edema of the feet
- C. Gastrointestinal upset
- D. Chloasma
Correct Answer: A
Rationale: The nursing diagnosis of Ineffective Tissue Perfusion is related to thromboembolism, which is a complication of estrogen replacement therapy. A nurse may note other female hormone-related adverse reactions such as edema of the feet due to excess fluid volume or gastrointestinal upset, which manifests as nausea, vomiting, abdominal cramps, and bloating. Chloasma is a dermatologic reaction due to female hormones, riposo in excessive pigmentation of the skin.
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