RN NCLEX Practice Test Related

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A client with gallstones and obstructive jaundice is experiencing severe itching. The physician has prescribed cholestyramine (Questran). The client asks, “How does this drug work?” What is the nurse’s best response?

  • A. “It blocks histamine, reducing the allergic response.”
  • B. “It inhibits the enzyme responsible for bile excretion.”
  • C. “It decreases the amount of bile in the gallbladder.”
  • D. “It binds with bile acids and is excreted in bowel movements with stool.”
Correct Answer: D

Rationale: Cholestyramine binds bile acids in the intestine, forming complexes excreted in stool, reducing circulating bile acids that cause itching. It doesn’t block histamine (A), inhibit enzymes (B), or reduce gallbladder bile (C).