Roach's Introductory Clinical Pharmacology 11th Edition - Upper Respiratory System Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Upper Respiratory System Drugs related questions and content

A client with vasomotor rhinitis has been prescribed an antihistamine. The client is eager to know whether the prescribed antihistamine may cause excessive sedation. Which antihistamine would the nurse identify as having very little sedative effect?

  • A. Brompheniramine
  • B. Clemastine
  • C. Chlorpheniramine
  • D. Azelastine
Correct Answer: D

Rationale: The nurse should assure the client that azelastine has very little sedative effect; it is a second-generation antihistamine with little effect on central nervous system (CNS) depression. Brompheniramine, clemastine, and chlorpheniramine are first-generation antihistamines. Sedation is seen more often with first-generation antihistamines.