Nokea
A dentist has detected symptoms of parodontosis in a patient. What antiprotozoal drug should be prescribed?
- A. Metronidazole
- B. Levamisole
- C. Griseofulvin
- D. Mykoseptin
Correct Answer: A
Rationale: The correct answer is A: Metronidazole. Parodontosis is a condition caused by bacterial infection, not protozoal infection. Metronidazole is an effective antibiotic commonly used to treat bacterial infections in the oral cavity, including those associated with parodontosis. Levamisole is an anthelmintic drug used to treat parasitic worm infections, not suitable for parodontosis. Griseofulvin is an antifungal medication used for fungal infections, not indicated for parodontosis. Mykoseptin is not a recognized drug and is likely a distractor. Therefore, based on the bacterial nature of parodontosis, Metronidazole is the appropriate choice.
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Koch apparatus uses temperature of:
- A. 90°C
- B. 95°C
- C. 100°C
- D. 110°C
Correct Answer: C
Rationale: The correct answer is C (100°C) because the Koch apparatus is used for sterilization, and the standard temperature for sterilization is 100°C. At this temperature, most microorganisms are killed, making it an effective method for sterilization. Choice A (90°C), B (95°C), and D (110°C) are incorrect because they are not commonly used temperatures for sterilization purposes. Choosing a temperature lower than 100°C may not effectively kill all microorganisms, while choosing a temperature higher than 100°C may lead to unnecessary energy consumption without providing additional sterilization benefits.
Which one of the following microbiological diagnostic methods is the most suitable for detection of genitourinary chlamydiosis
- A. cultural diagnostic
- B. ELISA
- C. CFT
- D. PCR
Correct Answer: D
Rationale: The correct answer is D: PCR. PCR (Polymerase Chain Reaction) is the most suitable method for detecting genitourinary chlamydiosis due to its high sensitivity and specificity in detecting the genetic material of Chlamydia trachomatis. PCR can detect even low levels of the pathogen, providing accurate results.
A: Cultural diagnostic is not as sensitive as PCR and may take longer to produce results.
B: ELISA detects antibodies, which may not be present in early stages of infection, leading to false-negative results.
C: CFT (Complement Fixation Test) is an older method with lower sensitivity compared to PCR for detecting chlamydiosis.
Which one is FALSE:
- A. Tissue samples and aspirations are better specimens than the swabs for diagnosis of skin and soft tissue infections
- B. To prove anaerobic agents. The specimen should be collected from the surface of the wound.
- C. The skin rash in some infections is due to the excessive production
- D. Healthy skin is an impenetrable barrier for the microorganisms
Correct Answer: B
Rationale: The correct answer is B because collecting specimens from the surface of a wound does not provide adequate samples for anaerobic agent detection. Anaerobic agents thrive in deep tissue environments with low oxygen levels, making surface specimens unreliable. Tissue samples and aspirations (choice A) are superior for diagnosing skin infections. Excessive production of toxins, not skin rash (choice C), causes symptoms in some infections. While healthy skin provides some protection, it is not completely impenetrable to microorganisms (choice D).
Which of the following(s) is/are the determinants of antigenicity?
- A. Chemical nature
- B. Size of the antigen
- C. Foreign origin
- D. All of these
Correct Answer: D
Rationale: The correct answer is D, as all options A, B, and C are determinants of antigenicity.
A: Chemical nature influences how the immune system recognizes antigens.
B: The size of the antigen affects its ability to be recognized by immune cells.
C: Antigens of foreign origin are more likely to trigger an immune response.
Therefore, all of these factors together play a crucial role in determining antigenicity.
Tularemia is caused by
- A. Francisella tularensis
- B. Bordetella pertussis
- C. Brucella suis
- D. Legionella sp.
Correct Answer: A
Rationale: Step-by-step rationale:
1. Tularemia is caused by Francisella tularensis, a highly infectious bacterium.
2. Francisella tularensis is the only pathogen specifically known to cause tularemia.
3. The other choices (Bordetella pertussis, Brucella suis, Legionella sp.) are not associated with tularemia.
4. Therefore, the correct answer is A - Francisella tularensis.