Nokea
A female client is prescribed norethindrone (Aygestin) The nurse understands that this drug is indicated for which of the following? Select all that apply.
- A. Treatment of amenorrhea
- B. Treatment of edema
- C. Treatment of endometriosis
- D. Pregnancy prevention
- E. Prevention of estrogen-dependent breast carcinoma
Correct Answer: A,C,D
Rationale: Progestins, like norethindrone (Aygestin), are used to treat amenorrhea, endometriosis, and functional uterine bleeding and to prevent pregnancy.
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An 80-year-old client with chronic renal insufficiency is prescribed anabolic steroid therapy for the management of anemia associated with renal insufficiency. The nurse understands that this client is at increased risk for which of the following?
- A. Hypoglycemic attacks
- B. Serious cardiac disease
- C. Hypotensive shock
- D. Cancer of the prostate
Correct Answer: D
Rationale: Elderly clients undergoing anabolic steroid therapy are at an increased risk of developing cancer of the prostate gland. Therefore, anabolic steroid therapy needs to be administered cautiously in these clients. Hypoglycemic attacks, serious cardiac disease, and hypotensive shock are not seen in elderly clients on anabolic steroid therapy.
A nurse is teaching a client about the use of estradiol (Estrace). The nurse wams the client of which of the following dermatologic reactions that may continue after drug discontinuation? Select all that apply.
- A. Dermatitis
- B. Stevens-Johnson syndrome
- C. Pruritus
- D. Chloasma
- E. Melasma
Correct Answer: D,E
Rationale: Chloasma and melasma are dermatologic reactions that can result from the use of estrogens, like estradiol (Estrace), and may continue when use of the drug is discontinued.
A client with delayed puberty has been advised to undertake transdermal androgen therapy, Androderm. Which of the following instructions should the nurse provide the client to help promote an optimal response to this therapy?
- A. Apply the Androderm to the underside of the scrotum.
- B. Repeat the application to the scrotum after 3 days.
- C. Moisten the skin before the application.
- D. Apply immediately after removing the cover.
Correct Answer: D
Rationale: Applying the system immediately after opening the pouch and removing the protective cover may help obtain an optimal response to the transdermal androgen delivery system. The drug should not be applied to the underside of the scrotum. It is applied to clean, dry skin on the abdomen, thigh, back, or upper arm. Thus, the skin should not be moistened before the application; rather, it should be dry. Seven days should be allowed between applications to a specific site, and application to the same site should not be repeated after 3 days.
A nurse is caring for a client receiving norethindrone for endometriosis. After administering the drug, the nurse would assess the client for which of the following? Select all that apply.
- A. Breast tenderness
- B. Edema
- C. Somnolence
- D. Hyperglycemia
- E. Thinning hair
Correct Answer: A,B
Rationale: Adverse reactions associated with norethindrone, a progestin, include breast tenderness, edema, insomnia, breakthrough bleeding, weight changes, and acne. Hyperglycemia and thinning hair are not associated with norethindrone.
A nurse is conducting a presentation for a young adult women's group about oral contraceptives and the risks. Which of the following would the nurse include as an increased risk?
- A. Fibrocystic breast disease
- B. Ovarian cysts
- C. Endometrial cancer
- D. Hepatic adenoma
Correct Answer: D
Rationale: The risks of hepatic adenoma may be increased with the use of oral contraceptives. Oral contraceptives also increase the risk of cardiovascular diseases, thromboembolic disorders, strokes, visual disturbances, gallbladder disease, hypertension, and fetal abnormalities. The risks of fibrocystic breast disease, ovarian cysts, and endometrial cancer are decreased, not increased, with the use of oral contraceptives.