A female patient consulted a doctor about a sense of epigastric discomfort, nausea and anorexia. A duodenal content analysis revealed lamblia. What drug should be prescribed?
- A. Metronidazole B.Chingamin C.Rifampicin D.Isoniazid E.Acyclovir
Correct Answer: A
Rationale: The correct answer is A: Metronidazole. Metronidazole is the drug of choice for treating Giardiasis caused by Giardia lamblia, which presents with symptoms such as epigastric discomfort, nausea, and anorexia. Metronidazole effectively targets and eliminates the parasite. Chingamin, Rifampicin, Isoniazid, and Acyclovir are not effective against Giardia lamblia and are used to treat other infections caused by different pathogens. Therefore, Metronidazole is the most appropriate choice in this scenario.
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A 10-year-old child cut his leg with a glass shard, when playing, and was delivered to outpatient department to receive anti-tetanus serum. To prevent development of anaphylactic shock the serum was introduced by Bezredka method. This method of organism hyposensitization is based on the following mechanism:
- A. Stimulation of antigen-specific IgG2
- B. Stimulation of the immunological antigen tolerance
- C. Binding of mast cell-fixed IgE
- D. Blocking of mast cell mediators synthesis
Correct Answer: C
Rationale: The correct answer is C: Binding of mast cell-fixed IgE. The Bezredka method involves introducing small amounts of the antigen to which the individual is allergic, leading to the binding of mast cell-fixed IgE. This process desensitizes the immune system and prevents anaphylactic shock by reducing the release of histamine and other mediators from mast cells.
Rationale:
1. A: Stimulation of antigen-specific IgG2 is incorrect because the Bezredka method primarily targets IgE, not IgG2.
2. B: Stimulation of the immunological antigen tolerance is incorrect as this method aims to block the allergic response rather than induce tolerance.
3. D: Blocking of mast cell mediators synthesis is incorrect because the Bezredka method does not directly inhibit the synthesis of mast cell mediators, but rather blocks their release by binding IgE.
Viruses can infect
- A. plants.
- B. bacteria.
- C. animals.
- D. all organisms.
Correct Answer: D
Rationale: The correct answer is D because viruses have the ability to infect all organisms, including plants, bacteria, animals, and even fungi. Viruses are non-living entities that require a host cell to replicate and spread. They can infect a wide range of organisms by attaching to specific receptors on the host cell's surface. Therefore, the correct answer is D as viruses have the capability to infect all living organisms. Choices A, B, and C are incorrect because viruses can infect not only plants, bacteria, and animals but also other organisms, making choice D the most comprehensive and accurate option.
The territory of an old burial ground for animal refuse that hasn't been used for over 50 years is meant for house building. But soil investigation showed the presence of viable spores of a causative agent causing a very dangerous disease. What microorganism might have been preserved in soil for such a long period of time?
- A. Bacillus anthracis
- B. Francisella tularensis
- C. Brucella abortus
- D. Yersinia pestis
Correct Answer: A
Rationale: The correct answer is A: Bacillus anthracis. This bacterium is known to form highly resistant spores that can survive for long periods in soil. Bacillus anthracis causes anthrax, a dangerous disease that can be transmitted to humans and animals. The other choices, Francisella tularensis, Brucella abortus, and Yersinia pestis, do not form spores as resistant as Bacillus anthracis. Therefore, only Bacillus anthracis is likely to have survived in the soil of the old burial ground for animal refuse for over 50 years.
The most common test for the diagnosis of Lyme borreliosis is:
- A. Widal agglutination test
- B. Cultivation on blood and chocolate agar
- C. ELISA, Western blot
- D. Ascoli thermoprecipitation test
Correct Answer: C
Rationale: The correct answer is C: ELISA, Western blot. These tests are commonly used for diagnosing Lyme borreliosis due to their high sensitivity and specificity in detecting antibodies against Borrelia burgdorferi, the causative agent. ELISA is the initial screening test, while Western blot is used for confirmation. Widal agglutination test (A) is used for diagnosing typhoid fever, not Lyme disease. Cultivation on blood and chocolate agar (B) is not commonly used for diagnosing Lyme borreliosis as Borrelia species are difficult to culture. Ascoli thermoprecipitation test (D) is used for diagnosing pneumonia caused by Streptococcus pneumoniae, not Lyme disease.
A mercury-containing compound used as a preservative in vaccines is:
- A. analgesic
- B. EDTA
- C. codeine
- D. thimerosal
Correct Answer: D
Rationale: The correct answer is D: thimerosal. Thimerosal is a mercury-containing compound used as a preservative in vaccines. It helps prevent contamination and growth of bacteria and fungi in multi-dose vials. Choice A, analgesic, refers to pain relievers, not preservatives. Choice B, EDTA, is a chelating agent used to bind metal ions and is not a preservative. Choice C, codeine, is an opioid pain medication and not a preservative used in vaccines. Thimerosal is the correct answer as it specifically fits the description of a mercury-containing compound used in vaccines.