Nokea
A group of students are reviewing antiparkinson drugs. They demonstrate understanding when they identify which of the following as classified as dopaminergic drugs? Select all that apply.
- A. Amantadine (Symmetrel)
- B. Bromocriptine (Parlodel)
- C. Biperiden (Akineton)
- D. Carbidopa (Lodosyn)
- E. Benztropine (Cogentin)
Correct Answer: A,B,D
Rationale: Amantadine (Symmetrel), bromocriptine (Parlodel), and carbidopa (Lodosyn) are classified as dopaminergic drugs. Biperiden and benztropine are cholinergic blocking drugs used to treat Parkinson's disease.
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A nurse is caring for a 70-year-old client who is receiving anticholinergic drug therapy for Parkinson's disease. The nurse would be alert for the development of which of the following in this client?
- A. Confusion and disorientation
- B. Choreiform movements
- C. Suicidal tendencies
- D. Psychotic episodes
Correct Answer: A
Rationale: The nurse should assess for confusion and disorientation when caring for this elderly client receiving anticholinergic drug therapy. Individuals older than 60 years frequently develop increased sensitivity to anticholinergic drugs and require careful monitoring. Lower doses may also be required in such cases. Choreiform movements, suicidal tendencies, and psychotic episodes are serious adverse reactions associated with the use of levodopa, which is a dopaminergic drug.
The nurse understands the need for cautious administration of the prescribed entacapone to a client with which of the following? Select all that apply.
- A. Hypotension
- B. Renal dysfunction
- C. Hepatic dysfunction
- D. Diabetes
- E. Hypertension
Correct Answer: A,B,C,E
Rationale: The nurse should cautiously administer entacapone (Comtan) to clients with hypotension, hypertension, and decreased hepatic or renal function.
A nurse is caring for a client who has been prescribed amaritadine for the treatment of the influenza A virus. After administration of the drug, the client complains of dry mouth. Which of the following instructions should the nurse offer the client to help relieve dry mouth?
- A. Instruct the client to take ice chips frequently.
- B. Encourage the client to take small, frequent meals.
- C. Instruct the client to avoid protein-rich foods.
- D. Stop the use of the antiparkinsonism drug by the client.
Correct Answer: A
Rationale: The nurse should instruct the client to suck on ice chips or hard candy (if allowed). The nurse should also instruct the client to take frequent sips of water throughout the day and between meals. The nurse encourages the client to have small, frequent meals when the client experiences a GI disturbance and not when the client complains of dry mouth. The nurse also need not instruct the client to avoid protein-rich foods because this will not reduce the client's discomfort due to dry mouth. The nurse should stop the use of the antiparkinsonism drug when the client complains of severe nausea or vomiting and not when the client is experiencing dry mouth. If dry mouth is so severe that there is difficulty in swallowing or speaking, or if loss of appetite and weight loss occur, the dosage of the antiparkinsonism drug may be reduced but not stopped completely.
A nurse is caring for a client who requires antiparkinson drug therapy. The nurse confirms that which of the following conditions is absent because it would contraindicate the use of the COMT inhibitor?
- A. Pregnancy
- B. Achalasia
- C. Peptic ulcers
- D. Glaucoma
Correct Answer: A
Rationale: The nurse should confirm that the client is not pregnant or lactating and that the client does not have a hypersensitivity to the drug to ensure that the use of COMT inhibitors is not contraindicated. Achalasia, peptic ulcers, and glaucoma are not conditions that are contraindications to the use of COMT inhibitors. The use of cholinergic blocking drugs is contraindicated in clients with achalasia, peptic ulcers, and glaucoma.
A nurse is caring for a 55-year-old client with Parkinson's disease who is prescribed entacapone. The nurse would monitor this client for which adverse reaction?
- A. Increased hand tremor
- B. Constipation
- C. Urinary retention
- D. Dyskinesia
Correct Answer: D
Rationale: The nurse should monitor for dyskinesia, which is an adverse reaction of the COMT inhibitors, in the client. The other adverse reactions include dizziness, hypersinesia, nausea, anorexia, diarrhea, orthostatic hypotension, sleep disorders, excessive dreaming, somnolence, and muscle cramps. A serious, and possibly fatal, adverse reaction that can occur with the administration of tolcapone, one of the COMT inhibitors, is liver failure. Increased hand tremor and constipation are adverse effects associated with the use of dopaminergic drugs. Urinary retention is an adverse reaction associated with the administration of cholinergic blocking drugs.