ATI Pharmacology Proctored Exam Related

Review ATI Pharmacology Proctored Exam related questions and content

A healthcare professional is planning to administer IV Alteplase to a client who is demonstrating manifestations of a massive Pulmonary Embolism. Which of the following interventions should the healthcare professional plan to take?

  • A. Administer IM Enoxaparin along with the Alteplase dose.
  • B. Hold direct pressure on puncture sites for up to 30 min.
  • C. Administer Aminocaproic acid IV prior to alteplase infusion.
  • D. Prepare to administer Alteplase within 8 hr of manifestation onset.
Correct Answer: B

Rationale: The correct intervention when administering IV Alteplase is to hold direct pressure on puncture sites for 10 to 30 minutes or until oozing of blood stops. This helps prevent bleeding complications associated with thrombolytic therapy. Administering IM Enoxaparin is not indicated with Alteplase, as it is an anticoagulant rather than a thrombolytic agent. Aminocaproic acid is not typically administered prior to alteplase infusion in the context of a massive Pulmonary Embolism. While timely administration of Alteplase is important, the specific timeframe within which it should be administered may vary based on the clinical situation, so a strict 8-hour window is not universally applicable.