Nokea
A journalist's body temperature has sharply increased in the morning three weeks after his mission in India, it was accompanied with shivering and bad headache. A few hours later the temperature decreased. The attacks began to repeat in a day. He was diagnosed with tropical malaria. What stage of development of Plasmodium is infective for anopheles-female?
Correct Answer: D
Rationale: The correct answer is D: Sporozoites. Sporozoites are the infective stage of Plasmodium for the female Anopheles mosquito. Here's the rationale: After being transmitted to a human host through a mosquito bite, the sporozoites travel to the liver where they mature and reproduce asexually as merozoites (not the infective stage for mosquitoes). The merozoites then infect red blood cells, leading to symptoms like fever, headache, and shivering. During the blood stage, some merozoites develop into male and female gametocytes, which are not infective to mosquitoes. When a mosquito bites an infected person, it ingests gametocytes, which then develop into male and female gametes and fuse to form ookinetes. Ookinetes develop into oocysts in the mosquito's gut, releasing sporozoites that migrate to the salivary glands, ready to infect a new human host when the mosquito bites