Nokea
A neonate exhibited some preliminary signs of infection, but the infants condition resolved spontaneously prior to discharge home from the hospital. This infants recovery was most likely due to what type of immunity?
- A. Cytokine immunity
- B. Specific immunity
- C. Active acquired immunity
- D. Nonspecific immunity
Correct Answer: D
Rationale: Natural immunity, or nonspecific immunity, is present at birth. Active acquired or specific immunity develops after birth. Cytokines are proteins that mediate the immune response; they are not a type of immunity.
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A patient is undergoing testing to determine the overall function of her immune system. What test can be performed to evaluate the functioning of the patients cellular immune system?
- A. Immunoglobulin testing
- B. Delayed hypersensitivity skin test
- C. Specific antibody response
- D. Total serum globulin assessment
Correct Answer: B
Rationale: Cellular (cell-mediated) immunity tests include the delayed hypersensitivity skin test, since this immune response is specifically dependent on the cellular immune response. Each of the other listed tests assesses functioning of the humoral immune system.
A woman has been diagnosed with breast cancer and is being treated aggressively with a chemotherapeutic regimen. As a result of this regimen, she has an inability to fight infection due to the fact that her bone marrow is unable to produce a sufficient amount of what?
- A. Lymphocytes
- B. Cytoblasts
- C. Antibodies
- D. Capillaries
Correct Answer: A
Rationale: The white blood cells involved in immunity (including lymphocytes) are produced in the bone marrow. Cytoblasts are the protoplasm of the cell outside the nucleus. Antibodies are produced by lymphocytes, but not in the bone marrow. Capillaries are small blood vessels.
A nurse has admitted a patient who has been diagnosed with urosepsis. What immune response predominates in sepsis?
- A. Mitigated
- B. Nonspecific
- C. Cellular
- D. Humoral
Correct Answer: D
Rationale: Most immune responses to antigens involve both humoral and cellular responses, although only one predominates. For example, during transplantation rejection, the cellular response predominates, whereas in the bacterial pneumonias and sepsis, the humoral response plays the dominant role. Neither mitigated nor nonspecific cell response is noted in this situation.
A patient is vigilant in her efforts to take good care of herself but is frustrated by her recent history of upper respiratory infections and influenza. What aspect of the patients lifestyle may have a negative effect on immune response?
- A. The patient works out at the gym twice daily.
- B. The patient does not eat red meats.
- C. The patient takes over-the-counter dietary supplements.
- D. The patient sleeps approximately 6 hours each night.
Correct Answer: A
Rationale: Rigorous exercise or competitive exercise usually considered a positive lifestyle factor can be a physiologic stressor and cause negative effects on immune response. The patients habits around diet and sleep do not present obvious threats to immune function.
A patient is responding to a microbial invasion and the patients differentiated lymphocytes have begun to function in either a humoral or a cellular capacity. During what stage of the immune response does this occur?
- A. The recognition stage
- B. The effector stage
- C. The response stage
- D. The proliferation stage
Correct Answer: C
Rationale: In the response stage, the differentiated lymphocytes function in either a humoral or a cellular capacity. In the effector stage, either the antibody of the humoral response or the cytotoxic (killer) T cell of the cellular response reaches and connects with the antigen on the surface of the foreign invader. In the recognition stage, the recognition of antigens as foreign, or non-self, by the immune system is the initiating event in any immune response. During the proliferation stage the circulating lymphocytes containing the antigenic message return to the nearest lymph node.