Roach's Introductory Clinical Pharmacology 11th Edition - Urinary Tract Anti-Infectives and Other Urinary Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Urinary Tract Anti-Infectives and Other Urinary Drugs related questions and content

A nurse is administering methenamine to a client with a UTI. Which of the following would the nurse instruct the client to avoid?

  • A. Ascorbic acid
  • B. Sodium bicarbonate
  • C. Acetaminophen
  • D. Ibuprofen
Correct Answer: B

Rationale: An increased urinary pH (alkaline urine) decreases the effectiveness of methenamine. Therefore, to avoid raising the urine pH when taking methenamine, the client should not use antacids containing sodium bicarbonate or sodium carbonate.