Gastrointestinal NCLEX RN Questions Related

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A nurse is caring for a client who is admitted to the emergency department with an acetaminophen overdose. The primary action of N-acetylcysteine in the treatment of acetaminophen overdose is

  • A. Inhibition of hepatic enzymes
  • B. Binding to acetaminophen metabolites
  • C. Enhancement of renal excretion
  • D. Stimulation of hepatic regeneration
Correct Answer: B

Rationale: N-acetylcysteine replenishes glutathione, which binds to toxic acetaminophen metabolites, preventing liver damage. It does not inhibit enzymes, enhance renal excretion, or stimulate regeneration directly.