A nurse is caring for a client with nocturnal enuresis. A physician has prescribed desmopressin acetate to the client. The nurse would assess the client for which of the following as a possible adverse reaction?
- A. Nasal congestion
- B. Breast tenderness
- C. Fluid retention
- D. Gynecomastia
Correct Answer: A
Rationale: The nurse should monitor for nasal congestion, abdominal cramps, headache, and nausea in the client as the adverse reactions to desmopressin acetate. When the client is administered gonadotropin, the nurse needs to monitor for fluid retention and gynecomastia as the adverse reactions to the drug. When choriogonadotropin alfa is administered to the client, the nurse should monitor for breast tenderness, ovarian overstimulation, and vasomotor flushes as the adverse reactions to the drug.
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Which of the following drugs might a nurse administer to a female client with fertility problems to help increase her chances of becoming pregnant? Select all that apply.
- A. Vasopressin (Pressyn)
- B. Clomiphene (Clomid)
- C. Octreotide (Sandostatin)
- D. Cetrorelix (Cetrotide)
- E. Gonadotropin (Menopur)
Correct Answer: B,D,E
Rationale: A nurse might administer clomiphene (Clomid), cetrorelix (Cetrotide), or gonadotropin (Menopur) to a female client with fertility problems to help increase her chances of becoming pregnant.
A client receiving gonadotropin therapy comes to the clinic for follow-up. Which of the following would the nurse immediately report to the primary health care provider? Select all that apply.
- A. Ascites
- B. Abdominal distention
- C. Abdominal pain
- D. Weight gain
- E. Irritability
Correct Answer: A,B,C
Rationale: The client is at risk for ovarian enlargement manifested by abdominal distention, pain, and ascites (with serious cases). The nurse would immediately notify the primary health care provider and the drug would be discontinued at the first sign of ovarian stimulation or enlargement. Weight gain and irritability would not need to be reported immediately.
A client is receiving treatment with adrenocorticotropic hormone. The nurse would instruct the client to avoid receiving which vaccine? Select all that apply.
- A. Zostavax (shingles)
- B. Meruvax (rubella)
- C. Td (tetanus and diphtheria)
- D. Fluzone (influenza)
- E. Attenuvax (measles)
Correct Answer: A,B,E
Rationale: Clients taking ACTH should avoid any vaccination with live virus including Zostavax, Meruvax, and Attenuvax.
A nurse is reviewing the medical history report of a client who is to receive gonadotropins. In which of the following conditions would the use of gonadotropins be contraindicated?
- A. Sensitivity to benzyl alcohol
- B. Epiphyseal closure
- C. Adrenal dysfunction
- D. Epilepsy
Correct Answer: C
Rationale: While reviewing the medical history of the client, the nurse should identify that gonadotropins are contraindicated in clients with adrenal dysfunction, high gonadotropin levels, thyroid dysfunction, liver disease, abnormal bleeding, ovarian cysts, sex-hormone-dependent tumors, or organic intracranial lesions (pituitary tumors). Gonadotropins should be used cautiously in clients with epilepsy. Somatropin growth hormones are contraindicated in clients with sensitivity to benzyl alcohol, epiphyseal closure, and underlying cranial lesions.
A nurse suspects that a client taking short-term high-dose methylprednisolone (Medrol) is developing Cushing's syndrome based on assessment of which of the following? Select all that apply.
- A. Weight loss
- B. Moon face
- C. Buffalo hump
- D. Dry skin
- E. Hypotension
Correct Answer: B,C
Rationale: A nurse should monitor a client taking short-term high-dose methylprednisolone (Medrol) for signs and symptoms of Cushing's syndrome, which include buffalo hump, moon face, oily skin, acne, osteoporosis, purple striae on the abdomen and hips, altered skin pigmentation, and weight gain.
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