Roach's Introductory Clinical Pharmacology 11th Edition - Antidiabetic Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Antidiabetic Drugs related questions and content

A nurse is caring for a client with type 2 diabetes receiving a meglitinide. The nurse reviews the clients medical record based on the understanding that which condition would contraindicate the use of this drug?

  • A. Diabetic ketoacidosis
  • B. Kidney disease
  • C. Severe heart failure
  • D. Liver disease
Correct Answer: A

Rationale: Meglitinides are contraindicated in clients with diabetic ketoacidosis and severe endocrine disease. Thiazolidinediones are contraindicated in clients with severe heart failure and used with caution in clients with kidney disease, severe heart failure, and liver disease.