A nurse is determining the estimated date of delivery for a pregnant client using Nagele's rule and notes documentation that the date of the client's last menstrual period was August 30, 2013. The nurse determines the estimated date of delivery to be which date?
- A. ########
- B. 6-Jun-14
- C. 6-Jul-14
- D. 6-May-14
Correct Answer: B
Rationale: Nagele's rule is a method used to estimate the date of delivery for pregnant clients. The rule involves subtracting 3 months and adding 7 days to the date of the first day of the last normal menstrual period, then adjusting the year. Subtracting 3 months from August 30, 2013, brings the date to May 30, 2013; adding 7 days results in June 6, 2013. Finally, after correcting the year, the estimated date of delivery is June 6, 2014. Therefore, the correct answer is June 6, 2014. Choices A, C, and D are incorrect because they do not follow the accurate calculation based on Nagele's rule.
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The chemotherapeutic DNA alkylating agents such as nitrogen mustards are effective because they:
- A. cross-link DNA strands with covalent bonds between alkyl groups on the drug and guanine bases on DNA.
- B. have few, if any, side effects.
- C. are used to treat multiple types of cancer.
- D. are cell-cycle-specific agents.
Correct Answer: A
Rationale: Alkylating agents are highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning, replication, and transcription. Choice 2 is incorrect because alkylating agents have numerous side effects including alopecia, nausea, vomiting, and myelosuppression. Choice 3 is incorrect because nitrogen mustards have a broad spectrum of activity against chronic lymphocytic leukemia, non-Hodgkin's lymphoma, and breast and ovarian cancer, but they are effective chemotherapeutic agents because of DNA crosslinkage. Choice 4 is incorrect because alkylating agents are non-cell-cycle-specific agents.
The physician wants to know if a client is tolerating his total parenteral nutrition. Which of the following laboratory tests is likely to be ordered?
- A. triglyceride level
- B. liver function tests
- C. a glucose tolerance test
- D. a complete blood count
Correct Answer: B
Rationale: The liver is the primary organ for digestion. Liver function tests measure the blood level of enzymes produced by the liver to assess tolerance of total parenteral nutrition.
The tendency of a drug to combine with its receptor is called:
- A. potency.
- B. efficacy.
- C. kinetics.
- D. affinity.
Correct Answer: D
Rationale: Affinity is a close relationship, mutual attraction, or similarity. The tendency of a drug to combine with its receptor is called affinity. Affinity is a measure of the strength of the drug-receptor bonding. Potency and efficacy describe the capability of a drug to produce the desired effect. Kinetics is the branch of science that deals with the effects of forces on the motions of material bodies or with changes in a physical or chemical system.
Which of the following arterial blood gas values indicates a patient may be experiencing a condition of metabolic acidosis?
- A. PaO2 (90%)
- B. Bicarbonate 15
- C. CO(2) 47 mm Hg
- D. pH 7.34
Correct Answer: B
Rationale: The bicarbonate value is below normal (15, normal range 22-26 mEq/L), indicating a condition of metabolic acidosis.
Immediately after delivery, the nurse assesses the woman's uterine fundus. At what location does the nurse expect to be able to palpate the fundus?
- A. At the level of the umbilicus
- B. Two centimeters above the umbilicus
- C. Midway between the symphysis pubis and umbilicus
- D. In the pelvic cavity
Correct Answer: C
Rationale: The correct answer is midway between the symphysis pubis and the umbilicus. Immediately after delivery, the uterus is about the size of a large grapefruit or softball. The fundus can be palpated at this location but then rises to a level just above the umbilicus before sinking to the level of the umbilicus, where it remains for about 24 hours. After 24 hours, the fundus starts descending gradually. By the 10th to 14th day, the fundus is in the pelvic cavity and cannot be palpated abdominally. Choices A and B are incorrect as the fundus is not initially at the level of the umbilicus or 2 centimeters above it. Choice D is also incorrect as the fundus does not remain in the pelvic cavity immediately after delivery.
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