Roach's Introductory Clinical Pharmacology 11th Edition - Antihypertensive Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Antihypertensive Drugs related questions and content

A nurse is instructing a client about his prescribed antihypertensive therapy with captopril. Which of the following instructions would the nurse include in the teaching plan? Select all that apply.

  • A. Taking the drug with meals to decrease GI upset
  • B. Informing the client about the possibility of a cough
  • C. Crushing the capsule before taking it
  • D. Taking measures to reduce injury from hypotension
  • E. Reporting any swelling of the face, throat, or extremities
Correct Answer: B,D

Rationale: The client needs to know that some clients experience a dry cough that does not subside until drug therapy is discontinued and this reaction may need to be tolerated. In addition, these drugs may cause a significant drop in blood pressure after the first dose, so the client needs to take measures to reduce the risk of injury from the drug's effects. The ACE inhibitors, captopril and moexipril, should be taken 1 hour before or 2 hours after meals to enhance absorption. The drugs are sustained-release capsules that should not be crushed, opened, or chewed. ACEIs do not cause angioedema.