Nokea
A nurse is preparing a presentation for a local community group about over-the-counter analgesics, including NSAIDs. Which of the following would the nurse integrate into the presentation as a serious risk with this class of drugs?
- A. Increased granulocyte count
- B. Cardiovascular thrombosis
- C. Increased WBC count
- D. Sickle cell anemia
Correct Answer: B
Rationale: A serious risk involved with the use of NSAIDs is cardiovascular thrombosis. Increased granulocyte count, increased WBC count, or sickle cell anemia is not caused by NSAIDs. Sickle cell anemia results from an inherited abnormality of hemoglobin. NSAIDs may cause decreased granulocyte count, decreased WBC count, or aplastic anemia.
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A nursing instructor is preparing a class discussion on the use of NSAIDs and interactions with other drugs. The instructor would emphasize that the effects of which of the following can increase with NSAID therapy? Select all that apply.
- A. Lithium
- B. Cyclosporine
- C. Furosemide
- D. Lisinopril
- E. Phenytoin
Correct Answer: A,B,E
Rationale: The use of NSAIDs can increase the effectiveness of lithium, cyclosporine, and phenytoin, possibly leading to toxicity.
A client comes to the clinic complaining of muscle aches and asks the nurse about using an over-the-counter NSAID. The client tells the nurse that he takes a medication to control his high blood pressure. The nurse cautions the client against using an NSAID while on antihypertensive drug therapy for which reason?
- A. It increases the metabolism of the antihypertensive drug.
- B. It increases absorption of the antihypertensive drug.
- C. It decreases the effectiveness of the antihypertensive drug.
- D. It decreases the metabolism of NSAIDs.
Correct Answer: C
Rationale: The nurse should inform the patient that taking an NSAID while on antihypertensive drug therapy decreases the effectiveness of antihypertensive drugs. Interactions of NSAIDs and antihypertensive drugs do not include increased metabolism of antihypertensive drugs, increased absorption of antihypertensive drugs, or decreased metabolism of NSAIDs.
A nurse is reviewing the medical record of a client who is diagnosed with migraine headaches. The history also reveals that the client has phenylketonuria. Which of the following would the nurse least expect to be prescribed as treatment for the client's migraine headaches? Select all that apply.
- A. Rizatriptan (Maxalt)
- B. Almotriptan (Axert)
- C. Eletriptan (Relpax)
- D. Sumatriptan (Imitrex)
- E. Zolmitriptan (Zomig)
Correct Answer: A,E
Rationale: Rizatriptan (Maxalt) and zolmitriptan (Zomig) are not used as treatment for migraines in a client with phenylketonuria because both medications contain phenylalanine.
A client who is receiving ibuprofen asks the nurse, 'What should I take the drug with?' Which of the following would the nurse suggest in the response? Select all that apply.
- A. Milk
- B. Orange juice
- C. Food
- D. Clear liquids
- E. Antacids
Correct Answer: A,C,E
Rationale: The nurse should advise the patient to take ibuprofen (Motrin) with food, milk, or antacids.
A nurse is providing care to a client who is receiving NSAIDs. The nurse would be especially alert for which of the following? Select all that apply.
- A. Oliguria
- B. Dysuria
- C. Hematuria
- D. Glucosuria
- E. Polyuria
Correct Answer: A,B,C,E
Rationale: Clients receiving NSAIDs should be monitored for the following renal adverse effects: polyuria, dysuria, oliguria, hematuria, eystitis, elevated BUN, and acute renal failure.