Roach's Introductory Clinical Pharmacology 11th Edition - Menopause and Andropause Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Menopause and Andropause Drugs related questions and content

A nurse is providing care to a client diagnosed with benign prostatic hypertrophy. The nurse understands that which of the following drugs inhibit the conversion of testosterone into 5-alpha-dihydrotestosterone (DHT), resulting in a decrease in prostate gland size? Select all that apply.

  • A. Terazosin (Hytrin)
  • B. Finasteride (Proscar)
  • C. Methyltestosterone (Testred)
  • D. Dutasteride (Avodart)
  • E. Doxazosin (Cardura)
Correct Answer: B,D

Rationale: Finasteride (Proscar) and dutasteride (Avodart) inhibit the conversion of testosterone into 5-alpha-dihydrotestosterone (DHT), which results in a decrease in prostate gland size, making them useful in the treatment of benign prostatic hypertrophy.