A nurse is providing care to a client experiencing hematologic failure. The nurse understands that this can include which of the following? Select all that apply.
- A. Anemia
- B. Bleeding
- C. Hypertension
- D. Infection
- E. Hypoglycemia
Correct Answer: A,B,D
Rationale: Hematologic failure results when inadequate numbers of blood cells are produced, leading to decreased oxygen transportation, blood coagulation, or inability for the body to prevent the invasion of microorganisms, which can lead to anemia, bleeding, and infection.
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A client with megaloblastic anemia is prescribed leucovorin. The nurse would identify which of the following as a contraindication for this drug?
- A. Pernicious anemia
- B. Hemochromatosis
- C. Uncontrolled hypertension
- D. Hypersensitivity to human albumin
Correct Answer: A
Rationale: Leucovorin is contraindicated in clients with pernicious anemia or other anemias in which vitamin B12 is deficient. Leucovorin is not contraindicated in clients with hemochromatosis, uncontrolled hypertension, and hypersensitivity to human albumin. Epoetin alfa is contraindicated in clients with uncontrolled hypertension and hypersensitivity to human albumin. Iron compounds are contraindicated in clients with hemochromatosis or hemolytic anemia.
After administering methoxy polyethylene epoetin beta, the nurse would be alert for the development of which of the following as a possible adverse reaction? Select all that apply.
- A. Bone pain
- B. Fluid retention
- C. Hypertension
- D. Fatigue
- E. Arthralgia
Correct Answer: C,D,E
Rationale: Hypertension, headache, nausea, vomiting, diarrhea, rashes, fatigue, arthralgia, and injection site skin reactions are adverse reactions the nurse should discuss with a client prior to the administration of methoxy polyethylene epoetin beta (Mircera).
A client is to receive oprelvekin (Neumega). After administering the drug, the nurse would be alert for which of the following as a possible adverse reaction? Select all that apply.
- A. Bone pain
- B. Fluid retention
- C. Syncope
- D. Nausea
- E. Fever
Correct Answer: B,C,E
Rationale: Fluid retention, peripheral edema, dyspnea, syncope, fever, and allergic reactions are adverse reactions associated with the administration of oprelvekin (Neumega).
A nurse should encourage a client with megaloblastic anemia to eat which of the following foods, as they are rich in folate? Select all that apply.
- A. Collard greens
- B. Grapes
- C. Wheat bread
- D. Salmon
- E. Chicken
Correct Answer: A,C,D,E
Rationale: A deficiency of folic acid (folate) results in megaloblastic anemia, and the nurse should encourage a client to eat foods rich in folic acid including leafy green vegetables (collard greens), fish (salmon), meat, poultry (chicken), and whole grains (wheat bread).
A nurse might administer epoetin alfa to a client with which type of anemia? Select all that apply.
- A. Anemia of chronic kidney disease
- B. Iron deficiency anemia
- C. Vitamin B12 deficiency anemia
- D. Anemia caused by cancer chemotherapy
- E. Anemia caused by zidovudine (AZT) therapy
Correct Answer: A,D,E
Rationale: Erythropoiesis-stimulating agents, like epoetin alfa, are used for anemia associated with the following: chronic kidney disease, cancer chemotherapy, zidovudine (AZT) therapy, and post-surgical replacement in place of allogeneic transfusions.
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