Nokea
A nurse is providing information to a client who has early Parkinson's disease and a new prescription for pramipexole. The nurse should instruct the client to monitor for which of the following adverse effects of this medication?
- A. Hallucinations
- B. Increased salivation
- C. Diarrhea
- D. Discoloration of urine
Correct Answer: A
Rationale: Pramipexole, a dopamine agonist, can cause hallucinations , especially in Parkinson's patients.
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You need to infuse 1,200 mL of a medication over 6 hours with a drop factor of 10 gtt/mL. Calculate the flow rate in drops per minute.
- A. 30 gtt/min
- B. 33 gtt/min
- C. 40 gtt/min
- D. 50 gtt/min
Correct Answer: B
Rationale: Flow rate = (1,200 mL 10 gtt/mL) ÷ (6 60) = 12,000 ÷ 360 = 33.33 gtt/min, rounded to 33 gtt/min (same as Q4).
The pharmacology students are learning about antibiotics that are known to cause photosensitivity in some patients. What nursing measures would ensure the comfort of patients taking these antibiotics and hopefully avoid serious adverse effects?
- A. Avoiding the use of aspirin and other over-the-counter pain products
- B. Getting a wig or other head cover to avoid heat loss
- C. Avoiding exposure to sunlight or use of a sunscreen and protective clothing if exposure is inevitable
- D. Providing frequent rest periods in a dark room
Correct Answer: C
Rationale: Photosensitivity from antibiotics increases sunburn risk; avoiding sunlight or using protection prevents serious skin reactions.
Plasma concentration of drug at time 0 is 96(g/ml). If t½ is 2 hours concentration in plasma at 10 hours will be
- A. 48
- B. 24
- C. 12
- D. 3
Correct Answer: D
Rationale: In first-order kinetics, the concentration halves every half-life (t½ = 2 hours). At 10 hours (5 half-lives), 96 → 48 → 24 → 12 → 6 → 3 µg/ml.
A young adult is receiving a maintenance dose of aminophylline, 3 mg/kg PO q6h. The patient weighs 50 kg. How much should the patient receive in a 24-hour period?
- A. 200 mg
- B. 400 mg
- C. 600 mg
- D. 800 mg
Correct Answer: C
Rationale: Use the formula, amount of drug prescribed weight of the patient in kg 4 (q6h in a 24-hour period = 4). 3 50 = 150 mg to be given every 6 hours. To determine how much the patient will receive in a 24-hour period, divide 6 into 24 to equal 4 doses. 4 150 = 600 mg.
Beta blockers are prescribed for diabetics with caution because of their ability to produce hypoglycemia and block the common symptoms of it. Which of the following symptoms of hypoglycemia is not blocked by these drugs and so can be used to warn diabetics of possible decreased blood glucose?
- A. Dizziness
- B. Increased heart rate
- C. Nervousness and shakiness
- D. Diaphoresis
Correct Answer: D
Rationale: Diaphoresis (sweating) is not blocked by beta blockers and signals hypoglycemia.