A nurse on a medical-surgical unit administers a hypnotic medication to an older adult client at 2100 . The next morning, the client is drowsy and wants to sleep instead of eating breakfast. Which of the following factors should the nurse identify as a possible reason for the client's drowsiness?
- A. Reduced cardiac function
- B. First pass effect
- C. Reduced hepatic function
- D. Increased gastric motility
Correct Answer: C
Rationale: Reduced hepatic function in older adults slows metabolism of hypnotics, prolonging drowsiness.
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A 24 year-old man with a history of substance abuse is suffering from generalized anxiety disorder. Which of the following drugs would be the most suitable for the management of his condition?
- A. Zolpidem
- B. Buspirone
- C. Midazolam
- D. Triazolam
Correct Answer: B
Rationale: Buspirone, a non-benzodiazepine, treats anxiety without dependence risk.
Choose the correct statement about ondansetron:
- A. It is a dopamine D2 receptor antagonist
- B. It suppresses postoperative nausea and vomiting
- C. It is the most effective antiemetic for motion sickness
- D. It is not effective by oral route
Correct Answer: B
Rationale: Ondansetron, a 5-HT3 receptor antagonist, effectively suppresses postoperative nausea and vomiting; it's less effective for motion sickness and is effective orally.
Influenza vaccine may be administered annually to:
- A. Patients with an egg allergy
- B. Pregnant patients
- C. Patients age 6 weeks or older
- D. Patients with acute febrile illness
Correct Answer: B
Rationale: Influenza vaccine is safe in pregnancy; egg allergy requires caution, 6 weeks is too young, and fever delays it.
Ciprofloxacin increases the toxicity of theophylline by
- A. Inhibiting metabolism
- B. Decreasing excretion
- C. Decrease seizure threshold
- D. Promote absorption
Correct Answer: B
Rationale: Ciprofloxacin reduces theophylline clearance, decreasing excretion.
Beta blocker are used in all, except
- A. Variant angina
- B. Mild hypertension
- C. Glaucoma
- D. Thyrotoxicosis
Correct Answer: A
Rationale: Beta-blockers worsen variant angina due to unopposed alpha constriction.