Roach's Introductory Clinical Pharmacology 11th Edition - Antiparkinson Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Antiparkinson Drugs related questions and content

A nurse reviews a client's medical record for possible conditions that would contraindicate the use of carbidopa/levodopa (Sinemet). Which of the following would the nurse identify as a contraindication? Select all that apply.

  • A. Narrow-angle glaucoma
  • B. Renal disease
  • C. Hepatic disease
  • D. Diabetes
  • E. Use of MAOI antidepressants
Correct Answer: A,E

Rationale: Carbidopa/levodopa (Sinemet) is contraindicated in clients who have known hypersensitivity to the drug or narrow-angle glaucoma or who use MAOI antidepressants.