Roach's Introductory Clinical Pharmacology 11th Edition - Upper Gastrointestinal System Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Upper Gastrointestinal System Drugs related questions and content

A nurse should monitor a client taking which of the following drugs for increased adverse effects and toxicity if omeprazole (Prilosec) therapy is initiated?

  • A. Phenobarbital (Luminal)
  • B. Digoxin (Lanoxin)
  • C. Diazepam (Valium)
  • D. Warfarin (Coumadin)
  • E. Ketoconazole (Nizoral)
Correct Answer: B,C,D

Rationale: The initiation of proton pump inhibitors, like omeprazole (Prilosec), can result in increased adverse reactions and toxicities of warfarin (Coumadin), benzodiazepines (diazepam), digoxin (Lanoxin), phenytoin (Dilantin), and clarithromycin (Biaxin).